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Extending the Dewanji and Kalbfleisch model to incorporate marker data

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Abstract

The model of Dewanji and Kalbfleisch for the estimation of time to tumour onset from a serial-sacrifice experiment is extended to include a marker state prior to the onset of the tumour. There are two versions of the model, one where a tumour is allowed to develop without the onset of marker, the other where a tumour develops after the marker but in which the marker later becomes unobservable.

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Authors and Affiliations

  1. Cancer Center, University of California, 94143-1297, San Francisco, CA, USA

    Alex McMillan

  2. Department of Epidemiology and Biostatistics, University of California, 94143-1297, San Francisco, CA, USA

    Abraham Silvers

Authors
  1. Alex McMillan
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  2. Abraham Silvers
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McMillan, A., Silvers, A. Extending the Dewanji and Kalbfleisch model to incorporate marker data. Environ Ecol Stat 3, 189–206 (1996). https://doi.org/10.1007/BF00453007

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  • DOI: https://doi.org/10.1007/BF00453007

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