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Fluorescence in situ hybridization and Y ring chromosome

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Summary

Investigations by fluorescence in situ hybridization and a Y-specific probe (Y190) of a male patient with a Y ring chromosome, 46,X,r(Y) showed four bright fluorescent spots within the ring. Thus, using this technique, it is possible to suggest that the ring originates from the duplication of the short arms of the Y chromosome.

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Authors and Affiliations

  1. Paediatric Research Unit, United Medical and Dental Schools of Guy's and St. Thomas Hospitals, 7th Floor Guy's Tower, Guy's Hospital, London Bridge, SE1 9RT, London, UK

    Robert Kozma, Claudine Fear & Matteo Adinolfi

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  1. Robert Kozma
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  2. Claudine Fear
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  3. Matteo Adinolfi
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Kozma, R., Fear, C. & Adinolfi, M. Fluorescence in situ hybridization and Y ring chromosome. Hum Genet 80, 95–96 (1988). https://doi.org/10.1007/BF00451465

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  • DOI: https://doi.org/10.1007/BF00451465

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