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Methylmethacrylate blood levels in patients with femoral neck fracture

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Summary

The blood levels of monomeric methylmethacrylate were measured in 20 patients with fracture of the femoral neck, treated with a Thompson prosthesis under spinal anesthesia. Monomeric methylmethacrylate was detected in the blood stream in all patients; the maximum levels (mean 6.441μg/ml, range 0.05–31.891μg/ml) were measured 30 s after insertion of the Thompson prosthesis. A moderate drop in systolic blood pressure and a marked reduction of arterial oxygen tension was noted after cementation and insertion of the prosthesis; the mean maximum drops were 10.1 mm Hg (range 0–32 mm Hg) and 6.1 mm Hg (range 0–13.5 mm Hg) No dose-dependent correlation could be established between the levels of monomeric methylmethacrylate and the drop in arterial blood pressure or arterial oxygen tension.

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Authors and Affiliations

  1. Department of Anaesthesia, Töölö Hospital, Helsinki University Central Hospital, Topeliuksenkatu 5, 00260, Helsinki 26, Finland

    N. Svartling & L. Tarkkanen

  2. Institute of Occupational Health, Helsinki, Finland

    P. Pfäffli

Authors
  1. N. Svartling
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  2. P. Pfäffli
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  3. L. Tarkkanen
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Svartling, N., Pfäffli, P. & Tarkkanen, L. Methylmethacrylate blood levels in patients with femoral neck fracture. Arch. Orth. Traum. Surg. 104, 242–246 (1985). https://doi.org/10.1007/BF00450218

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  • DOI: https://doi.org/10.1007/BF00450218

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