Archives of Microbiology

, Volume 142, Issue 2, pp 200–203 | Cite as

Effect of 2-deoxyglucose, α-methylglucoside, and glucosamine on aflatoxin production by Aspergillus parasiticus

  • Robert L. Buchanan
  • Lori A. Ocker
  • Heidi G. Stahl
Short Communications

Abstract

The effects of 2-deoxyglucose (2-DOG), α-methylglucoside (α-MG), and glucosamine (GA) on aflatoxin production by Aspergillus parasiticus were studied using conidia-initiated and replacement cultures. In conidia-initiated, 2-DOG, α-MG, and GA supported varying amounts of growth when employed as sole carbon sources. In both conidia-initiated and replacement cultures, 2-DOG, but not α-MG nor GA, as sole carbon sources support toxin formation. None of the compounds inhibited aflatoxin production when used in combination with glucose. It appears that neither 2-DOG, α-MG, nor GA can be considered nonmetabolizable analogs of glucose in A. parasiticus.

Key words

Aflatoxins Aspergillus parasiticus Glucose analogs 

Abbreviations

YES

yeast extract sucrose

PMS

peptone-mineral salts

2-DOG

L-deoxyglucose

α-MG

α-methylglucoside

GA

glucosamine

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References

  1. Buchanan RL, Ayres JC (1976) Effect of sodium acetate on growth and aflatoxin production by Aspergillus parasiticus NRRL 2999. J Food Sci 41:128–132Google Scholar
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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • Robert L. Buchanan
    • 1
  • Lori A. Ocker
    • 1
  • Heidi G. Stahl
    • 1
  1. 1.Eastern Regional Research Service, Agricultural Research ServiceU.S. Department of AgriculturePhiladelphiaUSA

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