Archives of Dermatological Research

, Volume 263, Issue 1, pp 67–73 | Cite as

Faecal porphyrin excretion in various types of porphyria

Thin layer chromatographic study
  • H. Perrot
  • M. Boucherat
  • J. Thivolet
Original Papers


A new method of thin layer chromatography was used for the study of faecal porphyrins in 31 porphyric patients (20 cases of porphyria cutanea tarda, 5 cases of porphyria variegata, 2 cases of hereditary coproporphyria, 1 case of acute intermittent porphyria and 3 cases of erythropoietic protoporphyria), 14 of their clinically normal relatives and 5 controls. The pattern obtained was characteristic of each type of porphyria and compared to previously published data.

Key words

Thin layer chromatography Porphyria Porphyrins Schlüsselwörter Dünnschichtchromatographie Porphyrie Porphyrine 


Eine neue dünnschichtchromatographische Methode wurde für die Untersuchung von Porphyrinen im Stuhl entwickelt. Es kamen 31 Patienten zur Untersuchung, davon 20 Patienten mit Porphyria cutanea tarda, 5 Patienten mit Porphyria variegata, 2 Patienten mit hereditärer Coproporphyrie, 1 Patient mit akuter intermittierender Porphyrie und 3 Patienten mit erythropoetischer Protoporphyrie. Weiterhin wurden klinisch unauffällige Verwandte der Porphyriker und 5 Kontrollen untersucht. Das Muster der Porphyrine war charakteristisch für jeden Typ der Porphyrie und wurde mit den früher publizierten Daten verglichen.


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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • H. Perrot
    • 1
  • M. Boucherat
    • 1
  • J. Thivolet
    • 1
  1. 1.Department of DermatologyHôpital Edouard HerriotLyon Cédex 2France

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