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Die Funktion der Nierenmembranen

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Abstract

Plasma membranes were isolated from rat kidney and their transport properties for sodium, calcium, protons, phosphate, glucose, lactate, and phenylalanine were investigated. The results demonstrate that the luminal plasma membrane, which is in contact with the primary urine, and the contraluminal plasma membrane, which is in contact with the interstitial fluid, differ in their content of ion-sensitive ATPases and sodium-cotransport systems. This allows conclusions on the mechanism of renal transport in which luminal and contraluminal membranes are arranged functionally in series.

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Authors and Affiliations

  1. Max-Planck-Institut für Biophysik, D-6000, Frankfurt (Main)

    R. Kinne

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  1. R. Kinne
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Additional information

Nach einem Vortrag bei der Tagung der Schweizerischen Akademie der Medizinischen Wissenschaften, Bern, Mai 1976.

Bei der Durchführung der Versuche und bei der Abfassung des Manuskriptes war mir die Unterstützung und Geduld meiner Frau, Dr. E. Kinne-Saffran, eine unentbehrliche Hilfe. Viele der in der Arbeit dargestellten Konzepte gehen auf fruchtbare Diskussionen mit Prof. Dr. K.J. Ullrich zurück, dem ich außerdem für seine ständige, interessierte Förderung meiner Arbeiten danke.

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Kinne, R. Die Funktion der Nierenmembranen. Naturwissenschaften 64, 326–334 (1977). https://doi.org/10.1007/BF00446787

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  • DOI: https://doi.org/10.1007/BF00446787

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