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Ring 11 chromosome (46,XX,r11(p15q25))

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A girl has a stable ring chromosome 11, which does not reveal loss of any chromosomal material. She demonstrates small stature, mild retardation, behavior problems, mild abnormal EEG, prominent sole furrows, increased deep tendon reflexes and hypothyroidism; this latter condition may have contributed to her retardation.

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Valente, M., Muller, H. & Sparkes, R.S. Ring 11 chromosome (46,XX,r11(p15q25)). Hum Genet 36, 345–350 (1977).

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