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European Journal of Pediatrics

, Volume 127, Issue 2, pp 67–73 | Cite as

Hemolytic pattern of erythrocytes in the newborn measured by the coil planet centrifuge system and its relationship to neonatal jaundice

  • Sachio Ogita
  • Tadahumi Shimamoto
  • Masanori Ohnishi
  • Teruji Kamei
  • Hideharu Noma
  • Osamu Ishiko
  • Tetsuji Ando
  • Tadashi Sugawa
Original Investigations

Abstract

Dynamic osmotic fragility of erythrocytes in cord blood and its changes during the neonatal period were studied by means of a coil planet centrifuge system. The starting-point for hemolysis in the newborn become similar to that of adult blood after approximately a week, while the shift of the end-point to the adult range required one month or more.

The percentage of fragile cord blood cells with a hemolysis starting-point above 110 m osmol and the maximum bilirubin level during neonatal period were examined. A high percentage of fragile cells was associated with high bilirubin levels, and when fragile cells comprised more than 7.0% of the total cord blood erythrocytes, the bilirubin level tended to rise above 15 mg/dl.

Key words

Dynamic osmotic fragility Coil planet centrifuge system Hemolysis in vivo Neonatal jaundice 

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References

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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • Sachio Ogita
    • 1
  • Tadahumi Shimamoto
    • 1
  • Masanori Ohnishi
    • 1
  • Teruji Kamei
    • 1
  • Hideharu Noma
    • 1
  • Osamu Ishiko
    • 1
  • Tetsuji Ando
    • 1
  • Tadashi Sugawa
    • 1
  1. 1.The Department of Obstetrics and GynecologyOsaka City University Medical SchoolOsakaJapan

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