Abstract
Dynamic osmotic fragility of erythrocytes in cord blood and its changes during the neonatal period were studied by means of a coil planet centrifuge system. The starting-point for hemolysis in the newborn become similar to that of adult blood after approximately a week, while the shift of the end-point to the adult range required one month or more.
The percentage of fragile cord blood cells with a hemolysis starting-point above 110 m osmol and the maximum bilirubin level during neonatal period were examined. A high percentage of fragile cells was associated with high bilirubin levels, and when fragile cells comprised more than 7.0% of the total cord blood erythrocytes, the bilirubin level tended to rise above 15 mg/dl.
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This study was aided by a grant from the Ministry of Health and Wellfare of Japan for research on handicapped children, 1976
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Ogita, S., Shimamoto, T., Ohnishi, M. et al. Hemolytic pattern of erythrocytes in the newborn measured by the coil planet centrifuge system and its relationship to neonatal jaundice. Eur J Pediatr 127, 67–73 (1978). https://doi.org/10.1007/BF00445762
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DOI: https://doi.org/10.1007/BF00445762