European Journal of Pediatrics

, Volume 146, Issue 4, pp 346–353 | Cite as

Endocrine control and disturbances of calcium and phosphate metabolism in children

  • K. Kruse


Most disorders of extracellular calcium and phosphate metabolism in childhood can be attributed to primary increased or decreased secretion/action of 1,25-dihydroxyvitamin D3 and parathyroid hormone or primary increased or decreased urinary excretion of phosphate and calcium. Based on this pathogenetic classification the most important diseases related to calcium and phosphate metabolism will be discussed.

Key words

Calcium metabolism Parathyroid hormone Phosphate metabolism Rickets Vitamin D metabolism 



parathyroid hormone


1,25-dihydroxyvitamin D3


25-hydroxyvitamin D3


24,25-dihydroxyvitamin D3


vitamin D deficiency rickets


vitamin D dependency rickets


multiple endocrine neoplasia






Albright's hereditary osteodystrophy


X-linked familial hypophosphataemic rickets


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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • K. Kruse
    • 1
  1. 1.Universitäts-KinderklinikWürzburgFederal Republic of Germany

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