European Journal of Pediatrics

, Volume 146, Issue 4, pp 346–353 | Cite as

Endocrine control and disturbances of calcium and phosphate metabolism in children

  • K. Kruse
Review

Abstract

Most disorders of extracellular calcium and phosphate metabolism in childhood can be attributed to primary increased or decreased secretion/action of 1,25-dihydroxyvitamin D3 and parathyroid hormone or primary increased or decreased urinary excretion of phosphate and calcium. Based on this pathogenetic classification the most important diseases related to calcium and phosphate metabolism will be discussed.

Key words

Calcium metabolism Parathyroid hormone Phosphate metabolism Rickets Vitamin D metabolism 

Abbreviations

PTH

parathyroid hormone

1,25(OH)2D3

1,25-dihydroxyvitamin D3

25(OH)D3

25-hydroxyvitamin D3

24,25(OH)2D3

24,25-dihydroxyvitamin D3

VDR

vitamin D deficiency rickets

VDDR

vitamin D dependency rickets

MEN

multiple endocrine neoplasia

HP

hypoparathyroidism

PHP

pseudohypoparathyroidism

AHO

Albright's hereditary osteodystrophy

XLH

X-linked familial hypophosphataemic rickets

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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • K. Kruse
    • 1
  1. 1.Universitäts-KinderklinikWürzburgFederal Republic of Germany

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