Skip to main content
SpringerLink
Log in

Biochemical processes under high hydrostatic pressure

Physico-chemical approaches to barosensitivity

  • Published:
Naturwissenschaften Aims and scope Submit manuscript

Abstract

High hydrostatic pressure may cause “metabolic dislocation” at the enzyme level or at the level of cellular processes. As shown by model studies, the underlying mechanisms include changes in quaternary structure and backbone conformation, modification of reactive groups, shifts of equilibria of protein-ligand association, among others. The given effects are connected with pressure-induced alterations of intra- and intermolecular interactions governing protein stability and macromolecular assembly. Changes in hydration are essential for both phenomena. Attempts to use available data to arrive at a clear-cut mechanism of barotolerance (or barophily) have failed so far. Due to the characteristics of deep-sea habitats, barophilic organisms are expected to require adaptation to both high pressure and low temperature, the latter being of greater importance.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bruun, A.: Nature 177, 1105 (1956)

    Google Scholar 

  2. Kinne, O. (ed.): Marine Ecology, Vols. 1–-5. New York: Wiley 1970–1980

    Google Scholar 

  3. Marshall, N.B.: Developments in Deep Sea Biology. Poole: Blandford 1979

    Google Scholar 

  4. Jaenicke, R.: Ann. Rev. Biophys. Bioeng. 10, 1 (1981)

    Google Scholar 

  5. Johnson, F.H., Eyring, H., Stover, B.J.: The Theory of Rate Processes in Biology and Medicine. New York: Wiley 1974

    Google Scholar 

  6. Marquis, R.E., Matsumara, P., in: Microbial Life in Extreme Environments, p. 105 (Kushner, D.J., ed.). London-New York-San Francisco: Academic Press 1978

    Google Scholar 

  7. ZoBell, C.E., Morita, R.Y.: J. Bact. 73, 563 (1957)

    Google Scholar 

  8. Yayanos, A.A., Dietz, A.S., van Boxtel, R.: Science 205, 808 (1979)

    Google Scholar 

  9. Lang, E.W., Lüdemann, H.-D.: Angew. Chem. 94, 351 (1982)

    Google Scholar 

  10. Frank, H.S.: Science 169, 635 (1970); Lawson, A.W., Hughes, A.J., in: High Pressure Physics and Chemistry, Vol. 1, p. 207 (Bradley, R.S., ed.). London-New York: Academic Press 1963

    Google Scholar 

  11. Horne, R.A., Courant, R.A.: J. Chem. Phys. 69, 2224 (1965)

    Google Scholar 

  12. Hills, G.J.: Symp. Soc. Exp. Biol. 26, 1 (1972)

    Google Scholar 

  13. Hawley, S.A.: Meth. Enzymol. 49, 15 (1978)

    Google Scholar 

  14. Zipp, A., Kauzmann, W.: Biochemistry 12, 4217 (1973)

    Google Scholar 

  15. Hvidt, A.: J. Theor. Biol. 50, 245 (1975); Bøje, L., Hvidt, A.: Biopolymers 11, 2357 (1972)

    Google Scholar 

  16. Richards, F.M.: Ann. Rev. Biophys. Bioeng. 6, 151 (1977)

    Google Scholar 

  17. Lauffer, M.A.: Entropy-Driven Processes in Biology. Berlin-Heidelberg-New York: Springer 1975

    Google Scholar 

  18. Jaenicke, R.: Eur. J. Biochem. 21, 110 (1971)

    Google Scholar 

  19. Jaenicke, R., Lüdemann, H.-D., Schade, B.: Biophys. Struct. Mech. 7, 195 (1981)

    Google Scholar 

  20. Kauzmann, W.: Adv. Protein Chem. 14, 1 (1959)

    Google Scholar 

  21. Hauer, H., et al.: FEBS Lett. 135, 135 (1981)

    Google Scholar 

  22. Jaenicke, R.: Biophys. Struct. Mech. 8, 231 (1982)

    Google Scholar 

  23. Jaenicke, R., Lauffer, M.A.: Biochemistry 8, 3083 (1969)

    Google Scholar 

  24. Sturtevant, J.M., et al.: ibid. 20, 3792 (1981)

    Google Scholar 

  25. Schuster, T.M., Scheele, R.B., Khairallah, L.H.: J. Mol. Biol. 127, 461 (1979)

    Google Scholar 

  26. Shire, S.J., Steckert, J.J., Schuster, T.M.: ibid. 127, 487 (1979)

    Google Scholar 

  27. Morild, E.: Adv. Protein Chem. 35, 93 (1981); Kauzmann, W., in: Proc. 4th Int. Conf. High Pressure, Kyoto (Heremans, K., ed.), p. 619 (1974); Suzuki, K., Taniguchi, Y.: Bull. Soc. Exp. Biol. 26, 103 (1972)

    Google Scholar 

  28. Tanford, C.: Adv. Protein Chem. 23, 122 (1968); 24, 1 (1970)

    Google Scholar 

  29. Schmid, G., Lüdemann, H.-D., Jaenicke, R.: Eur. J. Biochem. 86, 219 (1978)

    Google Scholar 

  30. Brandts, J.F., Halvorson, H.R., Brennan, M.: Biochemistry 14, 4953 (1975)

    Google Scholar 

  31. Kim, P.S., Baldwin, R.L.: Ann. Rev. Biochem. 51, 459 (1982)

    Google Scholar 

  32. Hauer, H., Lüdemann, H.-D., Jaenicke, R.: Z. Naturforsch. 37c, 51 (1982)

    Google Scholar 

  33. Landau, J.V., in: High Pressure Effects on Cellular Processes, p. 45 (Zimmerman, A.M., ed.). New York: Academic Press 1970; Morita, R.Y., Haight, R.D.: J. Bacteriol. 83, 1341 (1962)

    Google Scholar 

  34. Penniston, J.T.: Arch. Biochem. Biophys. 142, 322 (1971)

    Google Scholar 

  35. Jaenicke, R., Koberstein, R.: FEBS Lett. 17, 351 (1971)

    Google Scholar 

  36. Müller, K., Lüdemann, H.-D., Jaenicke, R.: Biophys. Chem. 14, 101 (1981)

    Google Scholar 

  37. Schade, B.C., et al: Biochemistry 19, 1121 (1980)

    Google Scholar 

  38. Schade, B.C., et al: Biophys. Chem. 11, 257 (1980)

    Google Scholar 

  39. Müller, K., Lüdemann, H.-D., Jaenicke, R.: Biochemistry 20, 5411 (1981)

    Google Scholar 

  40. Müller, K., Lüdemann, H.-D., Jaenicke, R.: Biophys. Chem. 16, 1 (1982)

    Google Scholar 

  41. Seifert, T., Bartholmes, P., Jaenicke, R.: ibid. 15, 1 (1982)

    Google Scholar 

  42. Jaenicke, R., Müller, K., Gäde, G.: Naturwissenschaften 68, 205 (1981)

    Google Scholar 

  43. Müller, K., Lüdemann, H.-D., Jaenicke, R.: ibid. 68, 524 (1981)

    Google Scholar 

  44. Schulz, E., Lüdemann, H.-D., Jaenicke, R.: FEBS Lett. 64, 40 (1976)

    Google Scholar 

  45. Schulz, E., Jaenicke, R., Knoche, W.: Biophys. Chem. 11, 253 (1976)

    Google Scholar 

  46. Kriss, A.E.: Marine Microbiology: Deep Sea, p. 91. New York: Wiley 1962

    Google Scholar 

  47. Low, P.S., Somero, G.N.: Comp. Biochem. Physiol. B52, 67 (1975)

    Google Scholar 

  48. Weber, G.: Proc. Conf. New Horizon Biochem., Nagoya 1980

Download references

Author information

Authors and Affiliations

  1. Institut für Biophysik und Physikalische Biochemie der Universität, D-8400, Regensburg

    Rainer Jaenicke

Authors
  1. Rainer Jaenicke
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Dedicated to Dr. Johannes Jaenicke on the occasion of his 95th birthday

This work was supported by the Deutsche Forschungsgemeinschaft (SFB 4) and the Fonds der Chemischen Industrie. I would like to thank Prof. H.-D Lüdermann and Drs. K. Müller, R. Rudolph, B.C. Schade, G. Schmid and T. Seifert for fruitful discussions and collaboration. The excellent technical assistance of I. Fuchs and the skilled cooperation of the mechanical workshop, especially R. Knott, G. Niesner, G. Wiesener and K. Zweckerl are gratefully acknowledged.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jaenicke, R. Biochemical processes under high hydrostatic pressure. Naturwissenschaften 70, 332–341 (1983). https://doi.org/10.1007/BF00444207

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00444207

Keywords

Search

Navigation