Abstract
Bone radiotracer uptake in renal osteodystrophy was investigated in 35 dialysis patients by correlating the results of quantitative bone scintigraphy with those of biochemical and bone morphometric studies. There were highly significant correlations (P<0.001) between the total skeletal activity and the biochemical (iPTH and alkaline phosphatase), and histologic parameters of hypeparathyroidism. These clinical results strongly suggest that increased bone turnover i.e. hyperparathyroidism, rather than osteomalacia is the major cause of increased skeletal uptake in renal osteodystrophy.
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de Graaf, P., te Velde, J., Pauwels, E.K.J. et al. Increased bone radiotracer uptake in renal osteodystrophy clinical evidence of hyperparathyroidism as the major cause. Eur J Nucl Med 7, 152–154 (1982). https://doi.org/10.1007/BF00443921
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DOI: https://doi.org/10.1007/BF00443921