Mycopathologia

, Volume 76, Issue 2, pp 115–117 | Cite as

Auxotrophic markers and the cytogenetics of Filobasidiella neoformans

  • M. T. Kline
  • E. S. Jacobson
Article
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Abstract

In the sexual phase of Cryptococcus neoformans four post-meiotic nuclei give rise to the nuclei of four long chains of basidiospores. If there is a fixed relationship between one post-meiotic nucleus and one chain the result should be genetic homogeneity within single chains; random composition of chains would represent the opposite case. We tested for homogeneity in single chains from crosses of niacin-auxotrophs to the wild type by dissecting single chains of basidiospores from mature fruiting bodies. Out of 14 chains, 11 were homogeneous; the probability of obtaining this result by random processes was <0.01. These results suggest that mitotic products of a particular post-meiotic nucleus may be channeled into a particular basidiospore chain.

Keywords

Random Process Fruiting Body Opposite Case Single Chain Cryptococcus Neoformans 

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References

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Copyright information

© Dr W. Junk Publishers 1981

Authors and Affiliations

  • M. T. Kline
    • 1
    • 2
  • E. S. Jacobson
    • 1
    • 2
  1. 1.Division of Infectious Diseases, Department of MedicineMedical College of Virginia - Virginia Commonwealth UniversityRichmondUSA
  2. 2.Research Service (151) McGuire Veterans Administration Medical CenterRichmondUSA

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