, Volume 76, Issue 2, pp 115–117 | Cite as

Auxotrophic markers and the cytogenetics of Filobasidiella neoformans

  • M. T. Kline
  • E. S. Jacobson


In the sexual phase of Cryptococcus neoformans four post-meiotic nuclei give rise to the nuclei of four long chains of basidiospores. If there is a fixed relationship between one post-meiotic nucleus and one chain the result should be genetic homogeneity within single chains; random composition of chains would represent the opposite case. We tested for homogeneity in single chains from crosses of niacin-auxotrophs to the wild type by dissecting single chains of basidiospores from mature fruiting bodies. Out of 14 chains, 11 were homogeneous; the probability of obtaining this result by random processes was <0.01. These results suggest that mitotic products of a particular post-meiotic nucleus may be channeled into a particular basidiospore chain.


Random Process Fruiting Body Opposite Case Single Chain Cryptococcus Neoformans 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Dr W. Junk Publishers 1981

Authors and Affiliations

  • M. T. Kline
    • 1
    • 2
  • E. S. Jacobson
    • 1
    • 2
  1. 1.Division of Infectious Diseases, Department of MedicineMedical College of Virginia - Virginia Commonwealth UniversityRichmondUSA
  2. 2.Research Service (151) McGuire Veterans Administration Medical CenterRichmondUSA

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