European Journal of Pediatrics

, Volume 136, Issue 3, pp 311–316 | Cite as

Dysplasia epiphysealis hemimelica—Trevor disease. Severe manifestations in a child

  • H. -R. Wiedemann
  • M. Mann
  • P. Spreter v. Kreudenstein
Case Reports


This report describes a case of “dysplasia epiphysealis hemimelica” with the first clinical manifestations at birth and increasing difference in the length of the lower extremities during infancy. The diagnosis was made at the age of 3 years when marked disability had already occurred. There was involvement of both legs and, to a lesser degree, the arms suggesting that this is a systemic disorder.

Key words

Bones, growth and development Bones, osteochondrodysplasias Epiphyses Skeletal system, dysplasia epiphysealis hemimelica Trevor disease 


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  1. 1.
    Caffey J (1956) Pediatric X-ray diagnosis. Year Book Med Pub, 3rd ed, ChicagoGoogle Scholar
  2. 2.
    Carlson DH, Wilkinson RH (1979) Variability of unilateral epiphyseal dysplasia (dysplasia epiphysealis hemimelica). Radiology 133:369–373Google Scholar
  3. 3.
    Fairbank TJ (1956) Dysplasia epiphysialis hemimelica (tarsoepiphysial aclasis). J Bone Jt Surg 38-B, 237–257Google Scholar
  4. 4.
    Fasting OJ, Bjerkreim I (1976) Dysplasia epiphysealis hemimelica. Acta Orthop Scand 47:217–225Google Scholar
  5. 5.
    Fontaine G, Maroteaux P, Farriaux J-P, Saint-Aubert P (1971) La dysplasie épiphysaire hémimélique. Sem Hôp 47: 861–865Google Scholar
  6. 6.
    Kettelkamp DB, Campbell CJ, Benfiglio M (1966) Dysplasia epiphysealis hemimelica. A report of fifteen cases and a review of the literature. J Bone Jt Surg 48-A:746–766Google Scholar
  7. 7.
    Mann M (1978) Zur Dysplasia epiphysealis hemimelica. Orthopäd Praxis 14:281–283Google Scholar
  8. 8.
    Maroteaux P (1974) Maladies osseuses de l'enfant. Flammarion, Paris, pp 107–108Google Scholar
  9. 9.
    Mouchet A, Belot J (1926) La tarsomégalie. J Radiol Electrol 10:289–293Google Scholar
  10. 10.
    Rechnagel K (1960) Dysplasia epiphysialis hemimelica. Acta Orthop Scand 29:236–245Google Scholar
  11. 11.
    Saxton HM, Wilkinson JA (1964) Hemimelic skeletal dysplasia. J Bone Jt Surg 46-B:608–613Google Scholar
  12. 12.
    Spranger J (1976) The epiphyseal dysplasias. Clin Orthopaedics 114:46–61Google Scholar
  13. 13.
    Spranger J, Langer LO, Wiedemann H-R (1974) Bone dysplasias. An atlas of constitutional disorders of skeletal development. G. Fischer, Stuttgart 1974; W. B. Saunders, Philadelphia, pp 191–193Google Scholar
  14. 14.
    Trevor D (1950) Tarso-epiphysial aclasis: a congenital error of epiphysial development. J Bone Jt Surg 32-B:204–213Google Scholar
  15. 15.
    Wolfgang GL, Heath RD (1976) Dysplasia epiphysealis hemimelica. Clin Orthopaedics 116:32–34Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • H. -R. Wiedemann
    • 1
  • M. Mann
    • 2
  • P. Spreter v. Kreudenstein
    • 1
  1. 1.Department of PediatricsUniversity of KielKielFRG
  2. 2.Department of OrthopaedicsUniversity of KielGermany

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