Abstract
Thrombocytopenia was observed in 10 (2.0%) of 486 children with Kawasaki disease. In nine of the ten, the minimal paltelet count of 94000±38000 (SD)/mm3 was seen on day 6.8±2.2 (SD) of illness and the platelet counts were elevated to the normal level in 1–2 weeks. Thrombocytopenia in the nine appeared to be caused via coagulation-mediated platelet consumption, while the remaining child was diagnosed as having idiopathic thrombocytopenic purpura. One of the two who had severe coagulation-mediated thrombocytopenia of less than 50000/mm3 developed coronary aneurysms persisting over 1 year.
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Abbreviations
- APTT:
-
Activated partial thromboplastin time
- ESR:
-
Erythrocyte sedimentation rate
- FDP:
-
Fibrinogen/fibrin degradation products
- ITP:
-
Idiopathic thrombocytopenic purpura
- PT:
-
Prothrombin time
- SD:
-
Standard deviation
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Hara, T., Mizuno, Y., Akeda, H. et al. Thrombocytopenia: a complication of Kawasaki disease. Eur J Pediatr 147, 51–53 (1988). https://doi.org/10.1007/BF00442611
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DOI: https://doi.org/10.1007/BF00442611