Histoplasmosis in purebred mice: Influence of genetic susceptibility and immune depression on treatment
These experiments demonstrate that susceptibility to Histoplasma infection of the mouse is dramatically influenced by genetic and immunologic factors, and that these factors appear to exert little influence on response to therapy. They further demonstrate that such influence may vary in different visceral organs. The explanation for these observations remains to be elucidated.
KeywordsDepression Genetic Susceptibility Histoplasmosis Visceral Organ Immunologic Factor
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