Abstract
In a child with trisomy-18 prenatal echocardiography demonstrated the presence of a ventricular septal defect with overriding aorta. In a previous anatomical study of 18 hearts with this malformation we found a 50% concurrence rate with trisomy-18. In case of prenatal echocardiographic detection of a ventricular septal defect with overriding aorta, we advise thorough ultrasound examination for additional malformations as seen in trisomy-18; subsequently this procedure should be completed by cytogenetic analysis of amniotic cells.
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Moene, R.J., Sobotka-Plojhar, M., Oppenheimer-Dekker, A. et al. Ventricular septal defect with overriding aorta in trisomy-18. Eur J Pediatr 147, 556–557 (1988). https://doi.org/10.1007/BF00441991
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DOI: https://doi.org/10.1007/BF00441991