European Journal of Pediatrics

, Volume 124, Issue 4, pp 257–260 | Cite as

Absence of spermatogonia in the Prader-Willi syndrome

  • Murray L. Katcher
  • Gerald J. Bargman
  • Enid F. Gilbert
  • John M. Opitz
Article

Abstract

Bilateral testicular biopsies in an 8 1/2 year old boy with the Prader-Willi syndrome showed total absence of spermatogonia. Similar findings in postpubertal cases (Wannarachue et al., 1975) suggest that testicular dysplasia is one of the reasons for hypogonadism in males with the Prader-Willi syndrome.

Key words

Prader-Willi syndrome Absent spermatogonia Testicular dysplasia Hypogonadism 

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References

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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Murray L. Katcher
    • 1
  • Gerald J. Bargman
    • 1
  • Enid F. Gilbert
    • 1
    • 2
  • John M. Opitz
    • 1
    • 3
  1. 1.Department of PediatricsUniversity of Wisconsin Center for Health Sciences and Medical SchoolMadisonUSA
  2. 2.Department of PathologyUniversity of Wisconsin Center for Health Sciences and Medical SchoolMadisonUSA
  3. 3.Wisconsin Clinical Genetics Center of the Department of Medical GeneticsUniversity of Wisconsin Center for Health Sciences and Medical SchoolMadisonUSA

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