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The effect of gonadotrophin releasing hormone analogue on height prognosis in growth hormone deficiency and normal puberty

Abstract

We have treated seven pubertal children, five (three female, two male) with growth hormone deficiency and two (one female, one male) with constitutional short stature with intranasal (D-Serine6) gonadotrophin releasing hormone (GnRH) analogue (Buserelin) for a mean of 0.84 years (range, 0.5–1.3). Treatment was successful in arresting pubertal development but there was no improvement in final height prognosis.

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Abbreviations

GnRH:

gonadotrophin releasing hormone

GH:

growth hormone

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Stanhope, R., Brook, C.G.D. The effect of gonadotrophin releasing hormone analogue on height prognosis in growth hormone deficiency and normal puberty. Eur J Pediatr 148, 200–202 (1988). https://doi.org/10.1007/BF00441401

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  • DOI: https://doi.org/10.1007/BF00441401

Key words

  • Puberty
  • Growth hormone deficiency
  • GnRH analogue
  • Height prognosis