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Effects of morphine and nalorphine upon tooth pulp thresholds of dogs in the alert and drowsy state

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Summary

The alteration of tooth pulp thresholds of dogs with chronically implanted electrodes was determined in the awake and drowsy states after morphine and nalorphine. The elevation in tooth pulp threshold was significantly greater after morphine than during the alert or drowsy state of the animal. Nalorphine antagonized this effect of morphine.

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Authors and Affiliations

  1. Department of Pharmacology, University of Michigan, Ann Arbor

    Jane E. Heng & Edward F. Domino

  2. Department of Pharmacology, Stanford University, Palo Alto, California, USA

    Jane E. Heng

Authors
  1. Jane E. Heng
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  2. Edward F. Domino
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Additional information

Supported in part by grant MY-2653, United States Public Health Service.

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Heng, J.E., Domino, E.F. Effects of morphine and nalorphine upon tooth pulp thresholds of dogs in the alert and drowsy state. Psychopharmacologia 1, 433–436 (1960). https://doi.org/10.1007/BF00441191

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  • DOI: https://doi.org/10.1007/BF00441191

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