Psychopharmacologia

, Volume 1, Issue 5, pp 389–392 | Cite as

Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone

Part IV influence of haloperidol (R 1625) and of chlorpromazine on the behaviour of rats in an unfamiliar “open field” situation
  • Paul A. J. Janssen
  • Anton H. M. Jageneau
  • Karel H. L. Schellekens
Original Investigations

Summary

Haloperidol (R 1625) is 50 to 100 times more active than chlorpromazine as an inhibitor of exploratory motor behaviour in rats. Emotional defaecation in rats is inhibited by both drugs at similar dose levels.

Keywords

Haloperidol Dose Level Chlorpromazine Motor Behaviour Similar Dose 

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Copyright information

© Springer-Verlag 1960

Authors and Affiliations

  • Paul A. J. Janssen
    • 1
  • Anton H. M. Jageneau
    • 1
  • Karel H. L. Schellekens
    • 1
  1. 1.Research Laboratorium Dr. C. JanssenBeerseBelgium

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