Abstract
The estimation of total sugar, lactic acid and pH and sugar chromatography of the stool was done in 168 normal children and children suffering from malabsorption syndromes and diarrhea. No significant difference of the parameters between normals and patients could be established.
Zusammenfassung
Im Stuhl von 135 gesunden Frühgeborenen, Neugeborenen, Säuglingen und Kleinkindern und im Stuhl von 28 Kindern mit Diarrhoe wurden bestimmt: Gesamtzuckergehalt, Milchsäurekonzentration, pH und dünnschichtchromatografisch die Zuckerspektren. Es konnte gezeigt werden, daß weder die Altersgruppen untereinander noch die gesunden Kinder gegenüber den Kindern mit Diarrhoe signifikante Unterschiede in einem der untersuchten Parameter boten. Es wird gefolgert, daß die Diagnose einer Zuckermalabsorption aus diesen Parametern nicht zu stellen ist.
Similar content being viewed by others
References
Abraham, J. M., Levin, B., Oberholzer, V. G., Russel, A.: Glucose-galactose malabsorption. Arch. Dis. Childh. 42, 592 (1967)
Andersen, D. H.: Celiac syndrome; determination of fat in faeces; reliability of 2 chemical methods and of microscopic estimate; excretion of faeces and of fecal fat in normal children. Amer. J. Dis Child. 69, 141 (1945)
Auricchio, S., Dahlquist, A., Mürset, G., Prader, A.: Isomaltose intolerance causing decreased ability to utilize dietary starch. J. Pediat. 62, 165 (1963)
Auricchio, S., Prader, A., Mürset, G., Witt, G.: Saccharoseintoleranz: Durchfall infolge hereditären Mangels an intestinaler Saccharaseaktivität. Helv. paediat. Acta 16, 483 (1961)
Auricchio, S., Rubino, A., Mürset, G.: Intestinal glycosidase activities in the human embryo, fetus, and newborn. Pediatrics 35, 944 (1965)
Baar, S., Bickel, H.: Oligosaccharides in infants faeces. J. clin. Path. 17, 273 (1964)
Carredu, P., Giovannini, M., Cevini, G.: Vorübergehende Disaccharidintoleranz bei den Ernährungsstörungen des Säuglingsalters. Helv. paediat. Acta 18, 97 (1963)
Clarke, A. D., Podmore, D. A.: The enzymatic determination of lactic acid in faeces in galactosidase deficiency. Clin. chim. Acta 13, 725 (1966)
Coello-Ramirez, P., Lifshitz, F.: Enteric microflora and carbohydrate intolerance in infants with diarrhea. Pediatrics 49, 233 (1972)
Davidson, A. G. F., Mullinger, M.: Reducing substances in neonatal stools detected by Clinitest. Pediatrics 46, 632 (1970)
Durand, P., Martino, A. M., Lamedica, G. M.: Diagnosis of carbohydrate intolerance diarrheas by stool chromatography. Lancet 1961 II, 374
Feldheim, G., Schmidt, E. F., Haenel, H.: Über die Besiedlung des Meconiums. Zbl. Bakt., I. Abt. Orig. 177, 62 (1960)
Ford, J. D., Haworth, J. C.: The fecal excretion of sugars in children. J. Pediat. 63, 988 (1963)
Gorbach, S. L., Nahas, L., Lerner, P. I., Weinstein, L.: Studies on intestinal microflora: I. Effects of diet, age, and periodic sampling on numbers of fecal microorganisms in man. Gastroenterology 53, 845 (1967)
Gryboski, J. D., Zillis, J., Ma, O. H.: A study of fecal sugars by high voltage electrophoresis. Gastroenterology 47, 26 (1964)
György, P.: Biochemical aspects (the uniquness of human milk). Amer. J. clin. Nutr. 24, 970 (1971)
Holzel, A., Schwarz, V., Sutcliffe, K. W.: Defective lactose absorption causing malnutrition in infancy. Lancet 1959 I, 1126
Hooft, C., Devos, E., Kriekemans, J., van Damme, J.: Malabsorption and diabetes mellitus in children. Helv. paediat. Acta 23, 478 (1968)
Ichihashi, Y.: Colonization of bacteria in man. J. Jap. med. Ass. 67, 702 (1972)
Kaijser, K., Öckermann, P. A.: Diagnostic problems in glucose galactose malabsorption. Acta paediat. scand. 59, 214 (1970)
Kerry, K. R., Anderson, C. M.: A ward test for sugar in faeces. Lancet 1964 I, 981
Kraffczyk, F., Helger, R., Bremer, H. J.: Thin layer chromatographic screening tests for carbohydrate anomalies in plasma, urine and faeces. Clin. chim. Acta 42, 303 (1972)
Lentze, M., Schaub, J., Harms, K.: A simple and rapid thin-layer chromatographic method for the assay of intestinal disaccharidases. Clin. chim. Acta 33, 301 (1971)
Lentze, M.: Dünnschichtchromatographische Untersuchungen zur Diagnose von kindlichen Malabsorptionssyndromen. Med. Dissertation, München 1973, in press
Lifshitz, F., Coello-Ramirez, P., Contreras-Gutierrez, M. L.: The response of infants to carbohydrate oral loads after recovery from diarrhea. J. Pediat. 79, 612 (1971)
Lifshitz, F., Coello-Ramirez, P., Gutierrez-Topete, G., Cornado-Cornet, M. C.: Carbohydrate intolerance in infants with diarrhea. J. Pediat. 79, 760 (1971)
Lindquist, B.: Die intestinale Monosaccharid-Malabsorption. Mschr. Kinderheilk. 117, 18 (1969)
Lindquist, B., Meeuwisse, G. W.: Chronic diarrhea caused by monosaccharid-malabsorption. Acta paediat. scand. 51, 674 (1962)
Linneweh, F.: Isotopen-Anwendung bei der Erforschung erblicher Stoffwechselkrankheiten. Mschr. Kinderheilk. 118, 191 (1970)
Malpress, F. H., Hytten, F. E.: The oligosaccharides in human milk. Biochem. J. 68, 708 (1958)
Mayer, J. B., Tewes, G., Pluta, U., Dittmann, J.: Zum Stoffwechsel des Bact. bifidum. VIII. Mitteilung. Typenbestimmung unserer Stämme. Z. Kinderheilk. 94, 141 (1965)
McMichael, H. B., Webb, J., Dawson, A. M.: Lactase deficiency in adults: A cause of functional diarrhea. Lancet 1965 I, 717
Meeuwisse, G. W., Melin, K.: Glucose galactose malabsorption. Acta paediat. scand., Suppl. 188, 3 (1969)
Roe, J.: The determination of sugar in blood and spinal fluid with anthrone reagent. J. biol. Chem. 212, 335 (1955)
Rosebury, T.: Microorganisms indigenous to man, pp. 435. New York: McGraw Hill 1962
Sinterhauf, K., Mayer, J. B., Dittmann, J.: Zum Stoffwechsel des Bact. bifidum. IX. Mitteilung. Abbau von Kohlenhydraten durch Bact. bifidum. Z. Kinderheilk. 97, 146 (1966)
Soeparto, P., Stobo, E. A., Walker-Smith, J. A.: Role of chemical examination of the stool in diagnosis of sugar malabsorption in children. Arch. Dis. Childh. 47, 56 (1972)
Stahl, E.: Dünnschichtchromatographie. Berlin-Heidelberg-New York: Springer 1967
Tomaszewski, L., Hofmann, H., Brozozowska, I., Zalewski, T.: Lactic acid excretion with stools by premature babies, newborns, infants, and healthy children. Pediat. pol. 46, 13 (1971)
Tabaqchali, S., Booth, C. C.: Relationship of the intestinal bacterial flora to absorption. Brit. med. Bull. 23, 285 (1967)
Torres-Pinedo, R., Lavastida, M., Rivera, C. L., Rodriguez, H., Ortiz, A.: Studies on infant diarrhea: I. A comparison of the effects of milk feeding and intravenous therapy upon the composition and volume of the stool and urine. J. clin Invest. 45, 469 (1966)
Torres-Pinedo, R., Rivera, C. L., Fernandez, S.: Studies on infant diarrhea: II. Absorption of glucose and net fluxes of water and sodium chloride in a segment of the jejunum. J. clin. Invest. 45, 1916 (1966)
Visakorpi, J. K.: Die intestinale Disaccharid-Spaltung und ihre kongenitalen Störungen. Mschr. Kinderheilk. 117, 25 (1969)
Weidenhagen, R., Lorenz, S.: Palatinose (6-(α-Glucopyranosido)-fructofuranose), ein neues bakterielles Umwandlungsprodukt der Saccharose. Zeitschr. für die Zuckerindustrie 7, 533 (1957)
Weijers, H. A., Van de Kamer, J. H., Dicke, W. K., Ijesseling, J.: Diarrhea caused by deficiency of sugar splitting enzymes. Acta paediat. scand. 50, 55 (1961)
Zimprich, H., Lothaller, H.: Verlaufskontrolle beim Zöliakiesyndrom unter besonderer Berücksichtigung dünnschichtchromatographischer Methoden. Wien. klin. Wschr. 82, 253 (1970)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Schaub, J., Lentze, M. Sugars, lactic acid and pH in feces of children. A useful diagnostical approach for gastrointestinal disorders?. Z. Kinder-Heilk. 115, 141–153 (1973). https://doi.org/10.1007/BF00440539
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00440539