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Double-blind evaluation of the effect of acute amantadine on cocaine craving

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Abstract

Single doses of amantadine hydrochloride and placebo were administered in a double-blind cross-over design on separate days to ten actively craving cocaine abusers in treatment. Pharmacological treatment did influence cocaine craving, but amantadine was less effective than placebo.

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Authors and Affiliations

  1. Department of Psychiatry, Yale University School of Medicine, 06519, New Haven, CT, USA

    Frank H. Gawin, Charles Morgan, Thomas R. Kosten & Herbert D. Kleber

Authors
  1. Frank H. Gawin
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  2. Charles Morgan
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  3. Thomas R. Kosten
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  4. Herbert D. Kleber
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Gawin, F.H., Morgan, C., Kosten, T.R. et al. Double-blind evaluation of the effect of acute amantadine on cocaine craving. Psychopharmacology 97, 402–403 (1989). https://doi.org/10.1007/BF00439458

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  • DOI: https://doi.org/10.1007/BF00439458

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