Skip to main content
SpringerLink
Log in

Induction of fermentation in Crabtree-negative yeasts

  • Published:
Mycopathologia Aims and scope Submit manuscript

Abstract

The induction of fermentation was studied in Candida utilis, a Crabtree-negative, respiratory yeast. This process occurs under oxygen-limiting conditions in the presence of a fermentable substrate and is the result of de novo enzyme synthesis. Induction occurs at permissive growth temperatures and its inhibition at 45 ° C is accompanied by loss of ability to take up glucose. The ability to be induced to an increased fermentative state is characteristic of all Crabtree-negative yeasts observed with the exception of an obligate aerobe, Hansenula wingei. No similar process occurs in the Crabtree-positive yeasts.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bulder, C. J. E. A., 1964. Induction of petite mutation and inhibition of synthesis of respiratory enzymes in various yeasts. Antonie van Leeuwenhoek, J. Microbiol. Serol. 30: 1–9.

    Google Scholar 

  2. Chapman, C. & Bartley, W., 1968. The kinetics of enzyme changes in yeast under conditions that cause the loss of mitochondria. Biochem. J. 107: 455–465.

    Google Scholar 

  3. Colowick, S. P. & Kaplan, N. O. (eds.), 1960. Methods in Enzymology. Vol. 5. New York: Academic Press. pp. 500–501.

    Google Scholar 

  4. DeDeken, R. H., 1966. The Crabtree effect: A regulatory system in yeast. J. Gen. Microbiol. 44: 149–156.

    Google Scholar 

  5. Grant, D. W., Sinclair, N. A. & Nash, C. H., 1968. Temperature-sensitive glucose fermentation in the obligately psychrophilicyeast, Candida gelida, Can. J. Microbiol. 8: 1105–1110.

    Google Scholar 

  6. McClary, D. O. & Bowers, B. D., 1967. Structural differentiation of obligately aerobic and facultatively anaerobic yeasts. J. Cell Biol. 32: 519–524.

    Google Scholar 

  7. Moss, F. J., Rickard, P. A. D., Beeck, G. A. & Bash, F. E., 1969. The response of microorganisms to steady-state growth in controlled concentrations of oxygen and glucose. I. Candida utilis. Biotech. Bioeng. 11: 561–580.

    Google Scholar 

  8. Sinclair, N. A., 1978. Role of oxygen in the induction of fermentation in the obligately psychrophilic yeast Leucosporidium stokesii. Can. J. Microbiol. 24: 31–35.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Microbiology, University of Arizona, 85721, Tucson, AZ, USA

    S. G. Franzblau & N. A. Sinclair

Authors
  1. S. G. Franzblau
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. A. Sinclair
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Franzblau, S.G., Sinclair, N.A. Induction of fermentation in Crabtree-negative yeasts. Mycopathologia 82, 185–190 (1983). https://doi.org/10.1007/BF00439225

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00439225

Keywords

Search

Navigation