Summary
We present details of a family who show a high incidence of both intracranial saccular aneurysm and infundibular widening. Familial aneurysms are compared with aneurysms occurring in the general population with regard both to site distribution and age of onset of symptoms. The possibility of infundibular widening being preaneurysmal is further discussed. It is highly likely that the mode of inheritance in familial cases is one of dominance.
Similar content being viewed by others
References
O'Brien JG (1942) Subarachnoid haemorrhage in identical twins. Br Med J 16: 607–608
Chambers WR et al (1954) Familial incidence of congenital aneurysms of cerebral arteries. Reported cases of ruptured aneurysms in father and son. JAMA 155: 358–359
Sakai N et al (1974) Familial occurrence of intracranial aneurysms. Surg Neurol 2: 25–29
Hashimoto I (1977) Familial intracranial aneurysms and cerebral vascular anomalies. J Neurosurg 46: 419–427
Hassler O, Saltmann GF (1963) Angiographic and histological changes in infundibular widening of the posterior communicating artery. Acta Radiol [Diagn] (Stockh) 1: 321–327
Epstein F et al (1970) The clinical significance of junctional dilatation of the posterior communicating artery. J Neurosurg 33: 529–531
Drake CG (1966) On the surgical treatment of ruptured intracranial aneurysms. Clin Neurosurg 13: 122–155
Stuntz JT et al (1970) Radiographic and histologic demonstration of an aneurysm developing on the infundibulum of the posterior communicating artery. Case report. J Neurosurg 33: 591–595
Young B, et al (1971) Documented enlargement and rupture of a small arterial sacculation. J Neurosurg 34: 814–817
Yoshimoto G, Suzuki J (1974) Eight year demonstrated study of an aneurysms growth at the origin of the posterior communicating artery. Neurol Surg (Tokyo) 2: 571–573
Taveras JM, Wood EH (1976) Diagnostic neuroradiology, 2nd ed. Williams and Wilkins, Baltimore, p 585
Waga S, Morikawa A (1979) Aneurysm developing on the infundibular widening of the posterior communicating artery. Surg Neurol 11: 125–127
Patrick D, Appleby A (1982) Infundibular widening of the posterior communicating artery progressing to true aneurysm. (Submitted to) Br J Radiol
Edelsohn L et al (1972) Familial aneurysm and infundibular widening. Neurology (Minneapolis) 22: 1056–1060
Thierry A et al (1972) Les cas familiaux. D'aneurysmes intra craniens. Revue de la litterature et presentation d'une observation. Neurochirurgie 18: 267–276
McKusick VA (1978) Mendelian inheritance in man, 5 ed. Johns Hopkins Press, Baltimore, p 27
Fox JL, Ko JP (1980) Familial intracranial aneurysms. J Neurosurg 52: 501–503
Beumont PJV (1968) The familial occurrence of berry aneurysm. J Neurol Neurosurg Psychiatry 31: 399–402
Bentzen N (1972) Familial incidence of intracranial aneurysms. Case report. NZ Med J 75: 153–155
Sahs AL et al (1969) Intracranial aneurysms and subarachnoid haemorrhage. A cooperative study. Lippincott, Philadelphia
Saltzmann GF (1959) Infundibular widening of the posterior communicating artery studied by carotid angiography. Acta Radiol 51: 415–421
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Patrick, D., Appleby, A. Familial intracranial aneurysm and infundibular widening. Neuroradiology 25, 329–334 (1983). https://doi.org/10.1007/BF00439213
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00439213