Abstract
A remarkable outer cell-wall thickening (up to 1.5 μm) was observed on septate hyphae obtained from pus collected from multiple abscesses of a 25-year-old female patient. Ultrastructural examination of the hyphae showed a thick electron dense layer of microfibrillar material surrounding the electron transparent cell wall. The organism was able to grow only on hypertonic media upon initial isolation but on later subculture it grew on normal isotonic media. The thick microfibrillar material diminished progressively upon subculture but could be demonstrated in 7 day secondary cultures in isotonic liquid medium. There, microfibrillar bridges appeared to bind hyphae together. The observations suggested that this microfibrillar material was a true extracellular component. The immunological status of the patient was not examined, but her 10 year history of multiple mycotic abscesses and dermatophytoses suggested some abnormalities.
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References
Brown, J. P. & M. R. Edwards, 1971. Observations on budding cells of Torulopsis glabrata. Can. J. Microbiol. 17: 609–616.
Carbonell, L. M. & J. Rodriguez, 1968. Mycelium phase of Paracoccidioides brasiliensis and Blastomyces dermatitidis: an electron microscopic study. J. Bacteriol. 96: 533–543.
Carey, W. F., L. H. Musche & L. S. Baron, 1960. The formation of bacterial protoplasts in vivo J. Immun. 84: 183–188.
Lin, C. H. & C. H. Yuan, 1979. Mycotic abscess of paranasal sinuses and orbit. Plast. Reconstr. Surg. 63: 735–738.
Dienes, L. & H.J. Weinberger, 1951. The L-forms of bacteria. Bact. Rev. 15: 245–288.
Dodge, B. O., 1920. The life history of Ascobolus magnificus: origin of the ascocarp from two strains. Mycologia 12: 115–133.
Farley, J. F., R. A. Jersild & D. J. Niederprum, 1975. Origin and ultrastructure of intra-hyphal hyphae in Trichophyton terrestre and T. rubrum. Arch. Microbiol. 106: 195–200.
Garrison, R. G., 1983. Ultrastructural cytology of pathogenic fungi. In D. H. Howard, ed., Fungi pathogenic for humans and animals. Part A Biology. Marcel Dekker, Inc., New York and Basel: 229–322.
Gunasekaran, M., W. M. Hess & D. J. Weber, 1973. Ultrastructure and lipid changes in Pyrenochaeta terrestris during aging. Can. J. Microbiol. 19: 491–496.
Hess, W. M., 1969. Ultrastructure of onion roots infected with Pyrenochaeta terrestris, a fungus parasite. Amer. J. Bot. 56: 832–845.
Kendrick, W. B., A. Molnar, 1965. A new Ceratocystis and its Verticicladiella imperfect stages associated with the berk beetle Dryococtes confusus on Abies lasiocarpa. Can. J. Bot. 43: 39–43.
Lane, J. W. & R. G. Garrison, 1970. Electron microscopy of self-parasitism by Hisloplasma capsulatum and Blastomyces dermatitidis. Mycopathol. Mycol. Appl. 40: 271–276.
Lane, J. W., R. G. Garrison & M. F. Field, 1969. Ultrastructural studies on the yeastlike and mycelium phases of Sporotrichum schenckii. J. Bacteriol. 100: 1010–1019.
Louria, D. B., T. Kaminski, M. Grieco & J. Singer, 1969. Aberrant forms of bacteria and fungi found in blood or cerebrospinal fluid. Arch. Intern. Med. 124: 39–48.
Lowry, R. J., A. S. Sussman, 1966. Intrahyphal hyphae in ‘clock’ mutants of Neurospora. Mycologia 58: 541–548.
Marsella, R., R. Mercantini, A. Stefanini & L. Volterra, 1983. An atypical isolate of Aspergillus fumigalus from a man affected with a pulmonary disease. Mykosen 26: 201–206.
Mattingly, S. J., J. R. Dipersio, M. L. Higgins, G. D. Shockman, 1976. Unbalanced growth and macromolecular synthesis in Streptococcus mutans FA-1. Infect. Immun. 13: 941–948.
Mattman, L. H., 1968. L forms isolated from infections. In L. B. Guze (ed.), Microbial protoplasts, spheroplasts and L forms. Williams & Wilkins Co., Baltimore: 472 seq.
Murphy, J. A., M. Thompson & A. J. Pappelis, 1980. Ultrastructure Diplodia maydis grown on selected synthetic media. Mycopathologia 71: 171–191.
Steele, S. D. & T. W. Fraser, 1973. Ultrastructural changes during germination of Geotrichum candidum arthrospores. Can. J. Microbiol. 19: 1031–1034.
Urabe, H. & T. Izu, 1969. The ultrastructure of Trichophyton and a double cell wall in the hyphae. J. Invest. Dermatol. 52: 508–513.
Van Haute, J. & C. A. Saxton, 1971. Cell wall thickening and intracellular polysaccharide in microorganisms of dental plague. Caries Res. 5: 30–43.
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Sukroongreung, S., Thakerngpol, K. Abnormal form of Aspergillus terreus isolated from mycotic abscesses. Mycopathologia 91, 47–52 (1985). https://doi.org/10.1007/BF00437287
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DOI: https://doi.org/10.1007/BF00437287