Abstract
Feed samples from Iowa suspected of causing vomiting and enlarged vulva as well as mortalities of swine were examined for toxigenic fungi and mycotoxins Fusarium moniliforme Sheldon and F. moniliforme Sheldon var. subglutinans Wollenew. & Reink. accounted for 43% and 18.5%, respectively, of the total count of 4.75×105 propagules filamentous fungi per gram of swine feed, but representatives of various Penicillium spp. and Aspergillus spp. were also found. Eight isolates of F. moniliforme var. subglutinans from the feed produced 51–540 μg of moniliformin per g on cracked corn at 25°C for six weeks. Zearalenone was not detected in these corn fermentations. Eight isolates of F. moniliforme from the feed did not produce detectable amounts of either zearalenone or monoliformin on cracked corn. Moniliformin was not detected in the feed samples.
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Arai T, Ito T: Cytotoxicity and antitumor activity of fusariocins mycotoxins from Fusarium moniliforme, in Antimicrobial and Anticancer Chemotherapy, Proceedings of the 6th International Congress of Chemotherapy, Vol. 1, 87–97, University Park Press, Baltimore, MD, 1970.
Booth C: The genus Fusarium. Commonwealth Mycological Institute, Kew, England, 1971, 237 pp.
Beasley VR, Buck WB, Vesonder RF, Ellis JJ: Feed refusal in cattle associated with Fusarium moniliforme in corn. Vet Rec 111:393–394, 1982.
Burmeister HR, Ciegler A, Vesonder RF: Moniliformin, a metabolite of Fusarium moniliforme, NRRL 6322: purification and toxicity. Appl Environ Microbiol 37:11–13, 1979.
Eppley RM: Screening method for zearalenone, aflatoxin and ochratoxin. J Assoc Off Anal Chem 51:74–78, 1968.
Gelderblom WCA, Thiel PG, Marasas WFO, van der Merwe KJ: Natural occurrence of fusarin C, a mutagen produced by Fusarium moniliforme. J Agric Food Chem 32:1064–1067, 1984.
Haliburton JC, Vesonder RF, Lock TF, Buck WB: Equine leucoencephalomalacia (ELEM): A study of Fusarium moniliforme as an etiologic agent. Vet Human Toxicol 21:348–351, 1979.
Hidaka H, Nagatsu T, Takeya K, Takeuchi T, Suda H, Kojiri K, Matsuzak M, Umezawa H: Fusaric acid, a hypotensive agent produced by fungi. J Antibiotics 22:228–230, 1969.
Joffe AZ, Palti J, Arabel-Sherman R: Fusarium moniliforme Sheld. in Israel [Gibberella fujikori (Saw.) Wollenw.]. Mycopathologia 50:85–107, 1973.
Kellerman TS, Marasas WFO, Pienaar JG, Nade TW: A mycotoxicosis of equidae caused by Fusarium moniliforme Sheldon. Onderstepoort J Vet Res 39:205–208, 1972.
Kriek NPJ, Marasas PS, Steyn PS, Van Rensberg SJ, Steyn M: Toxicity of a moniliformin-producing strain of Fusarium moniliforme var. subglutinans isolated from maize. Food Cosmet Toxicol 15:579–587, 1977.
Marasas WFO, Kellerman TS, Pienaar JG, Naude TW: Leukoencephalomalacia: A mycotoxicosis of equidae caused by Fusarium moniliforme Sheldon. Onderstepoort J Vet Res 43:113–122, 1976.
Marasas WFO, Krieb NPJ, Fincham JE, van Rensburg SJ: Primary liver cancer and oesophagel basal cell hyperplasin in rats caused by Fusarium moniliforme. Int J Cancer 34:383–387, 1984.
Mirocha CJ, Christensen CM, Nelson GH: Biosynthesis of the fungal estrogen F-2 and a naturally occurring derivatives (F-3) by Fusarium moniliforme. Appl Microbiol 17:482–483, 1969.
Mirocha JC, Christensen CM, Nelson GH: F-2 (zearalenone) estrogenic mycotoxin from Fusarium. In: S Kadis, A Ciegler, SJ Ajl (eds.) Microbial toxins, Vol VII. Academic Press, New York, 1971, pp 107–138.
Nelson PE, Tousson TA, Marasas WFO: Fusarium species: An illustrated manual for identification. Pennsylvania State University Press, University Park, 1983, 193 pp.
Sharby TF, Templeton GE, Beasley JN, Stephenson EL: Toxicity resulting from feeding experimentally molded corn to broiler chicks. Poult Sci 52:1007–1014, 1973.
Thiel PG: A molecular mechanism for the toxic action of moniliformin, a mycotoxin produced by Fusarium moniliforme. Biochem Pharm 27:483–486, 1978.
Thiel PG, Meyer CG, Marasas WFO: Natural occurrence of moniliforme together with deoxynivalenol and zearalenone in Transkeian corn. J Agric Food Chem 30:308–312, 1982.
Thomas DM: Occurrence of two Fusarium species in two maize cultivars in West Africa. Mycologia 73:1004–1007, 1981.
Wiebe LA, Bjeldanes LF: Fusarin C, a mutagen from Fusarium moniliforme grown on corn. J Food Sci 46:1424–1426, 1981.
Wilson BJ, Maronpot RR: Causative fungus agent of leucoencephalomalacia in equine animals. Vet Rec 88:484–486, 1971.
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Vesonder, R.F. Moniliformin produced by cultures of Fusarium moniliforme var. subglutinans isolated from swine feed. Mycopathologia 95, 149–153 (1986). https://doi.org/10.1007/BF00437119
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DOI: https://doi.org/10.1007/BF00437119