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In situ absorption of aflatoxins in rat small intestine

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Abstract

To evaluate the rate at which the four main aflatoxins (aflatoxins B1, B2, G1 and G2) are able to cross the luminal membrane of the rat small intestine, a study about intestinal absorption kinetics of these mycotoxins has been made. In situ results obtained showed that the absorption of aflatoxins in rat small intestine is a very fast process that follows first-order kinetics, with an absorption rate constant (k a ) of 5.84±0.05 (aflatoxin B1), 4.06±0.09 (aflatoxin B2), 2.09±0.03 (aflatoxin G1) and 1.58±0.04 (aflatoxin G2) h−1, respectively.

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Ramos, A.J., Hernández, E. In situ absorption of aflatoxins in rat small intestine. Mycopathologia 134, 27–30 (1996). https://doi.org/10.1007/BF00437049

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