, Volume 96, Issue 2, pp 103–107 | Cite as

Potential therapeutic effect of yeast killer toxin

  • Luciano Polonelli
  • Rodolfo Lorenzini
  • Flavia De Bernardis
  • Giulia Morace


Experimental infections were produced in guinea pigs, rabbits and dogs with lesions similar to those seen in human seborrheic dermatitis and otitis externa by cutaneous application of cultures of Malassezia furfur and M. pachydermatis. Infected animals were treated by topical application of a concentrated yeast killer toxin (Hansenula anomala UCSC 25F). Clinical recovery as well as negative mycological test cultures of infected animals proved to the clearly associated with the treatment by the killer toxin.


Therapeutic Effect Dermatitis Topical Application Infected Animal Experimental Infection 
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Copyright information

© Martinus Nijhoff/Dr W. Junk Publishers 1986

Authors and Affiliations

  • Luciano Polonelli
    • 1
  • Rodolfo Lorenzini
    • 2
  • Flavia De Bernardis
    • 2
  • Giulia Morace
    • 1
  1. 1.Istituto di Microbiologia, Facoltà di Medicina e Chirurgia, ‘A. Gemelli’Università Cattolica del Sacro CuoreRome
  2. 2.Istituto Superiore di SanitàRomeItaly

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