Abstract
Exophiala jeanselmei was isolated from three esophageal cultures over an 11-month period at Lutheran General Hospital. We believe this provides evidence for a new site of isolation, since previous reports of the organism's incidence were confined to skin and lung. Case 1 is an eight-year-old female with a three-year history of gagging and vomiting. Esophagoscopy revealed a mass biopsied as vegetable material. Case 2 is a 66-year-old retired male with a history of obesity, diabetes and spinal stenosis. Following back surgery, the patient developed odynophagia. Esophageal biopsies showed ulceration and bacterial colonies with no evidence of fungus. Case 3 is a 62-year-old male gardener who is also a nail biter. Esophagoscopy revealed a gastro-esophageal stricture with reflux and evidence of a hiatus hernia. Material biopsied was consistent with Barrett's esophagus and evidence of fungi was seen. The esophageal mass of case 1 and the esophageal brushings of case 2 and 3 grew E. jeanselmei. Aspiration, reflux, and mechanical disruption of the esophageal mucosa are possible predisposing factors in colonization of esophageal lesions by this ubiquitous, normally low virulence organism.
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References
Cooper, B. H., 1980. Introduction to clinical mycology. In E. H. Lennette, A. Balows, W. J. Hausler, Jr. & J. P. Truant (eds.), Manual of Clinical Microbiology, 3rd ed. American Society for Microbiology, Washington, D.C.: 533–540.
Dixon, D. M., H. J. Shadomy & S. Shadomy, 1980. Dematiaceous fungal pathothens isolated from nature. Mycopathologia 70: 153–161.
Espinel-Ingroff, A., T. M. Kerkering & H. J. Shadomy, 1982. Isolation of dematiaceous pathogenic fungi from a feed and seed warehouse. J. Clin. Microbiol. 15: 714–719.
McGinnis, M. R. & A. A. Padhye, 1977. Exophiala jeanselmei, a new combination for Phialophora jeanselmei. Mycotaxon 70: 341–352.
McGinnis, M. R., 1978. Human pathogenic species of Exophiala, Phialophora, and Wangiella. In Scientific Publication No. 356. The black and white yeasts. Pan American Health Organization, Washington, D.C.: 37–59.
McGinnis, M. R., 1980. Dematiaceous fungi. In E. H. Lennette, A. Balows, W. J. Hausler, Jr. & J. P. Truant (eds.), Manual of Clinical Microbiology, 3rd ed. American Society for Microbiology, Washington, D.C.: 602–610.
Monroe, P. W. & W. E. Floyd, Jr., 1981. Chromohyphomycosis of the hand due to Exophiala jeanselmei (Phialophora jeanselmei, Phialophora gougerotii) — case report and review. J. Hand Surg. 6: 370–373.
Naveh, Y. & A. Friedman, 1976. A case of Rubinstein-Taybi syndrome. Clin. Pediatr. (Phila). 15: 779–783.
Neilsen, H. S., Jr., N. F. Conant, T. Weinberg & J. F. Reback, 1968. Report of a mycetoma due to Phialophora jeanselmei and undescribed characteristics of the fungus. Sabouraudia 6: 330–333.
Thammayya, A. & M. Sanyal, 1980. Exophiala jeanselmei causing mycetoma pedis in India. Sabouraudia 18: 91–95.
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Sautter, R.E., Bliss, M.D., Morrow, D. et al. Isolation of Exophiala jeanselmei associated with esophageal pathology — Three cases, laboratory and clinical features. Mycopathologia 87, 105–109 (1984). https://doi.org/10.1007/BF00436637
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DOI: https://doi.org/10.1007/BF00436637