Quality of Life Research

, Volume 2, Issue 3, pp 221–226 | Cite as

Interpretation of quality of life changes

  • E. Lydick
  • R. S. Epstein


The clinical significance of quality of life changes has little to do with the QOL as a measure, but is rather a reflection on the novelty of the measures and researcher's inexperience in their use. This article discusses possible ways of evaluating quality of life measures in terms of patient-clinician interactions and how the clinician can assess the importance of these changes of QOL in terms of treatment and management of disease.

Key words

Clinical significance epidemiological studies outcomes research quality of life 


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Copyright information

© Rapid Communications of Oxford Ltd 1993

Authors and Affiliations

  • E. Lydick
    • 1
  • R. S. Epstein
    • 1
  1. 1.Merck Research LaboratoriesPennsylvaniaUSA

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