, Volume 63, Issue 3, pp 311–312 | Cite as

Interactions between motor activity and stereotypy in cocaine-treated rats

  • Alok K. Bhattacharyya
  • S. N. Pradhan
Short Reports


Effect of a single administration of a dose (5, 10, or 15 mg/kg, i.p.) of cocaine hydrochloride on spontaneous motor activity (SMA) and stereotypy (ST), and interactions between these behaviors were investigated in rats. SMA showed peak increases within 10 min and at 120 min after cocaine injection. Drug-induced stereotypy was maximal during the interval between these two peaks in SMA. Several neurotransmitters may be involved in the interactions between SMA and ST.

Key words

Cocaine Spontaneous motor activity Stereotypy Behavioral interactions Rat 


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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Alok K. Bhattacharyya
    • 1
  • S. N. Pradhan
    • 1
  1. 1.Department of Pharmacology, College of MedicineHoward UniversityWashington, D.C.USA

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