Summary
During a period from 1971 to 1978 13 cases of limb tumours with suspected malignancy had a biopsy and depending on the result of histological examination of frozen sections a subsequent amputation in the same session. Material included 5 cases of osteogenic sarcoma, 3 cases of mesenchymal chondrosarcoma, 2 cases of synovial sarcoma and 3 tumours of other origin. In 11 cases the radical operation was performed in the same session and in 2 cases surgical intervention was delayed until after examination of the definitive sections.
Zusammenfassung
Die Autoren haben aufgrund intraoperativer histologischer Untersuchungen an gefrorenen Schnitten in den Jahren 1971–1978 in 13 Fällen von Tumoren an den Extremitäten, die verdächtige maligne Entartungen vorwiesen, eine Biopsie mit gleichzeitig geplanter Amputation durchgeführt.
Ihr Krankengut besteht aus 5 Fällen von osteogenen Sarkomas, 3 Fällen von mesenchymalen Chondrosarkomas, 2 Fällen von synovialen Sarkomas und 3 Tumoren anderen Ursprungs. Eine radikale Operation wurde in 11 Fällen in gleicher Sitzung durchgeführt, in 2 Fällen mußte jedoch das Resultat der endgültig histologischen Untersuchung abgewartet werden.
Es werden über Möglichkeiten Vorteile und Schwierigkeiten einer radikalen Operation mit der gleichzeitigen intraoperativ durchgeführten Biopsie berichtet.
Similar content being viewed by others
References
Ackerman LV, Spjut HJ (1962) Tumors of bone and cartilage. Armed Forces Institute of Pathology, Washington
Bahners W, Burkhardt K (1974) Klinisches Bild, Verlauf und Prognose maligner Synovialome. Chirurg 45:507–510
Bosch J (1969) Die Prognose des Knochensarkoms. Münch Med Wochenschr 111:1036–1040
Cameron HU, Kostuik JP (1974) A long term follow up of synovial sarcoma. J Bone Jt Surg 56-13:613–617
Coventry MB, Dahlin DC (1957) Osteogenic sarcoma. A critical analysis of 430 cases. J Bone Jt Surg 39-A:74–78
Dahlin DC (1957) Bone tumors. C.C. Thomas, Springfield
Dahlin DC (1978) Osteosarcoma of bone and a consideration of prognostic variables. Cancer Treat Rep 62:189–192
Enneking WF, Springfield DS (1977) Osteosarcoma. Orthop Clin N Am 8:785–803
Eyre Brooke AL (1969) Bone tumours, the clinician and prognosis. J Kuwait Med Ass 3:195–214
Graham WD (1966) Bone tumours. Butterworths, London
Hanslik L, Friebold G (1968) Möglichkeiten und Grenzen der chirurgischen Behandlung maligner mesenchymaler Tumoren des Bewegungsapparates. Z Orthop 104:489–500
Jacobs RL, Fox TA (1972) Neurilemoma of bone. A case report with a review of the literature. Clin Orthop 87:248–253
Jaffe HL (1958) Tumors and tumorous conditions of the bones and joints. H. Kimpton, London
Johnson LC (1953) A general theory of bone tumors. Bull NY Acad Med 29:164–171
Johnson RJ, Bonfiglio M, Cooper RR (1971) Osteosarcoma. Clin Orthop 78:314–322
Lee SM, Hajdu SI, Exelby PR (1974) Synovial sarcoma in children. Surg Gynec Obst 138:701–704
Lichtenstein L (1965) Bone tumors, 3rd ed. CV Mosby, Saint Louis
Liebegott G (1960) Die Morphologie der primären Knochengeschwülste. Verb Deut Orthop Ges 47:101–132
Murray JA (1977) Synovial sarcoma. Orthop Clin N Am 8:963–972
Ottolenghi CE (1955) Diagnosis of orthopaedic lesions by aspiration biopsy. Results of 1061 punctures. J Bone Jt Surg 37-A:443–464
Peers HJ (1934) Primary intramedullary neurogenic sarcoma of the ulna. A report of a case. Am J Path 10:811–820
Pepe AJ, Kuhlmann RF, Miller DB (1977) Mesenchymal chondrosarcoma. A case report. J Bone Jt Surg 59-13:256–258
Pieper M, Daum R (1975) Knochensarkome. Monatsschr Kinderheilk 133:384–387
Pratt CB, Rivera G, Shanks E (1977) Osteosarcoma during pregnancy. Obst Gynec 50:24–26
Price CH, Jeffree GM (1977) Incidence of bone sarcoma in SW England, 1946–1974, in relation to age, sex, tumour site and histology. Br J Cancer 36:511–522
Russell WO, Cohen J, Enzinger F, Hajdu SI, Heise H, Martin RG, Meissner W, Miller WT, Schmitz RL, Suit HD (1977) A clinical and pathological staging system for soft tissue sarcomas. Cancer 40:1562–1570
Salzer M, Knahr K (1976) Resection of malignant bone tumors. In: Proceedings of the 6th International Symposium of the Gesellschaft zur Bekämpfung der Krebskrankheiten Nordrhein-Westfalen, Düsseldorf, Oct 17–18, 1974. Springer, Berlin Heidelberg New York
Salvador AH, Beabout JW, Dahlin DC (1971) Mesenchymal chondrosarcoma — observations on 30 new cases. Cancer 28:605–615
Schajowicz F (1955) Aspiration biopsy in bone lesions. Cytological and histological techniques. J Bone Jt Surg 37-A:465–471
Sherman RS, Pearson TA (1948) The roentgenographic appearance of renal cancer metastasis in bone. Cancer 1:276–285
Sweetnam R (1975) The surgical management of primary osteosarcoma. Clin Orthop 111:57–64
Trifaud A, Meaty R () Prognostic et traitement des sarcomes osteogeniques. J Chir 104:185–193
Unni KK, Dahlin DC, McLeod RA, Pritchard DJ (1977) Intraosseous well-differentiated osteosarcoma. Cancer 40:1337–1347
Uribe-Botero G, Russell WO, Sutow W W, Martin RG (1977) Primary osteosarcoma of bone. A clinicopathologic investigation of 243 cases, with necropsy studies in 54. Am J Clin Pathol 67:427–435
Witt AN (1975) Chirurgische Behandlung der malignen Knochengeschwülste. Langenbecks Arch Chir 27:339–346
Woods CG (1972) Diagnostic orthopaedic pathology. Blackwell Scientific Publ, Oxford London Edinburgh Melbourne
Wu KK, Guise ER, Frost HM, Mitchell CM (1976) Osteogenic sarcoma. Report of 157 cases. Henry Ford Hosp Med J 24:213–242
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Aszódi, K., Glauber, A. & Csató, Z. The importance of rapid, intraoperative histological diagnosis in the radical surgical treatment of the malignant tumours of the limbs. Arch. Orth. Traum. Surg. 96, 123–130 (1980). https://doi.org/10.1007/BF00433291
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00433291