Skip to main content
Log in

Synovial deposit of osmic acid after intra-articular injection

Anatomical and radiologic study of a case

  • Case Reports
  • Published:
Virchows Archiv A Aims and scope Submit manuscript

Summary

An anatomical and radiologic study of a synovial autopsy specimen 32 months after an intra-articular injection of osmic acid for the local treatment of a rheumatoid synovitis.

Osmium deposits are seen within peripheral cells of a fat lobule and also in a few histiocytes of the scar tissue which replaced the rheumatoid synovitis. These osmium deposits in the fat cells are present in a sufficient quantity to give a radiologic opacity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Amini, D., Datiano, L., Gagnon, J., Laurin, C.A.: The use of intra-articular osmic acid to produce chemical synovectomy in rabbits. Clin. Orthop. 79, 164–172 (1971)

    Google Scholar 

  2. Boussina, I., Lagier, R., Ott, H., Fallet, G.H.: Osmium deposits detected by X-ray after synoviorthesis of the knee. Radiological, clinical and anatomical study. Scand. J. Rheum. 5, 53–59 (1976)

    Google Scholar 

  3. Boussina, I., Lagier, R., Ott, H., Fallet, G.H.: Radiological opacities of the knee after intra-articular injections of osmic acid. Radiol. Clin. (in press)

  4. Collan, Y., Lorincz, G., Laine, V.: Deposition of osmium in rheumatoid synovial tissue after intra-articular injection of osmic acid. A histological and electron microscopical study. Scand. J. Rheum. 1, 27–31 (1972)

    Google Scholar 

  5. Mottonen, M., Pantio, M., Nevalainen, T.: Effects of osmium tetroxide on the rabbit knee joint normal synovial membrane. Acta rheum. scand. 16, 121–129 (1970)

    Google Scholar 

  6. Weston, W.J., Anttila, P.: Radiographic appearance of osmium in the soft tissues of the knee in rheumatoid arthritis. Scand. J. Rheum. 1, 17–20 (1972)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lagier, R., MacGee, W. & Boussina, I. Synovial deposit of osmic acid after intra-articular injection. Virchows Arch. A Path. Anat. and Histol. 372, 237–244 (1976). https://doi.org/10.1007/BF00433282

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00433282

Keywords

Navigation