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Electron microscopy of thrombocytes in the orthotopic porcine liver homograft during the late rejection (phagocytosis of thrombocytes by Kupffer cells)

Summary

Electron microscopical observations of thrombocytes in the orthotopic porcine liver homograft in later stages after transplantation are described and demonstrated. The most remarkable finding was a phagocytosis of apparently unaltered thrombocytes by the Kupffer cells. Besides single or small groups of thrombocytes in the sinusoids with partly close topographical relations to the endothelial lining and intrasinusoidal accumulation of blood platelets were observed. The possible significance of these findings is discussed with particular reference to the long-term prognosis of liver transplantation.

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I should like to thank Miss H. Schütz and Mrs. A. Kästner for their most valuable technical assistance.

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Cossel, L. Electron microscopy of thrombocytes in the orthotopic porcine liver homograft during the late rejection (phagocytosis of thrombocytes by Kupffer cells). Virchows Arch. A Path. Anat. and Histol. 364, 265–273 (1974). https://doi.org/10.1007/BF00433078

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  • DOI: https://doi.org/10.1007/BF00433078

Keywords

  • Public Health
  • Microscopy
  • Electron Microscopy
  • Small Group
  • Liver Transplantation