Virchows Archiv A

, Volume 373, Issue 1, pp 23–35 | Cite as

Ultrastructural aspects of chondrodystrophia calcificans congenita (syndrome of Conradi-Hünermann)

  • C. Bosman
  • E. Bonucci
  • P. Gugliantini
  • L. Saguí
Article

Summary

An ultrastructural study of chondrodystrophia calcificans congenita is reported. Foci of initial calcification of cartilage are characterized by coexistence of three different types of crystals, probably due to abnormal proteoglycan composition of cartilage matrix. The calcification process in chondrodystrophia calcificans congenita is apparently not related to ‘matrix vesicles’ as it is in normal cartilage.

Key words

Chondrodystrophia calcificans congenita Cartilage calcification Ultrastructure of cartilage 

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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • C. Bosman
    • 1
  • E. Bonucci
    • 1
  • P. Gugliantini
    • 2
  • L. Saguí
    • 2
  1. 1.First Institute of PathologyRome UniversityRomeItaly
  2. 2.Bambino Gesù Pediatric HospitalRomeItaly

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