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Effects of pentobarbital on punished behavior: Persistent increases with chronic administration

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Abstract

Food maintained responding by pigeons was suppressed by response-dependent electric shock presentation (punishment). Administration of 5.6 mg/kg pentobarbital IM for 25 days and, later, 10.0 mg/kg pentobarbital for 30 days resulted in profound, sustained, dose-related increases in punished responding and shock presentation.

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Author notes

  1. Jeffrey M. Witkin & James E. Barrett

    Present address: Department of Psychiatry, School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, 20014, Bethesda, MD, USA

Authors and Affiliations

  1. Department of Psychology, University of Maryland, 20742, College Park, MD, USA

    Jeffrey M. Witkin & James E. Barrett

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  1. Jeffrey M. Witkin
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  2. James E. Barrett
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Witkin, J.M., Barrett, J.E. Effects of pentobarbital on punished behavior: Persistent increases with chronic administration. Psychopharmacology 75, 324–325 (1981). https://doi.org/10.1007/BF00432448

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  • DOI: https://doi.org/10.1007/BF00432448

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