Abstract
Intracerebroventricular administration of calcium severely depressed the locomotor activity of unanesthetized mice, producing ataxic gait and motor incoordination. Pretreatment with pentobarbital (30 mg/kg, IP) twice daily for 2 and 6 days partially reversed this effect of calcium, suggesting that calcium and pentobarbital may in part exert their depressant effect by a similar mechanism.
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Fung, Y.K., Uretsky, N.J. Effect of calcium on locomotor activity of mice. Psychopharmacology 68, 207–208 (1980). https://doi.org/10.1007/BF00432143
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DOI: https://doi.org/10.1007/BF00432143