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Psychopharmacology

, Volume 66, Issue 1, pp 87–91 | Cite as

The effect of housing and gender on preference for morphine-sucrose solutions in rats

  • Patricia F. Hadaway
  • Bruce K. Alexander
  • Robert B. Coambs
  • Barry Beyerstein
Original Investigations

Abstract

To determine whether opiate consumption is affected by laboratory housing, individually caged and colony rats were given a choice between water and progressively more palatable morphine-sucrose solutions. The isolated rats drank significantly more of the opiate solution, and females drank significantly more than males. In the experimental phase during which morphine-sucrose solution consumption was greatest, the isolated females drank five times as much, and the isolated males sixteen times as much morphine (mg/kg) as the colony females and males respectively.

Key words

Morphine Self administration Housing 

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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Patricia F. Hadaway
    • 1
  • Bruce K. Alexander
    • 1
  • Robert B. Coambs
    • 1
  • Barry Beyerstein
    • 1
  1. 1.Department of PsychologySimon Fraser UniversityBurnabyCanada

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