Abstract
The effects of naloxone on IV methyl-0henidate-induced mood, behavior, and neurohumoral changes were assessed in eight psychiatric inpatients. While methylphenidate alone produced anticipated changes, the indications for significant naloxone-methylphenidate interactions were minimal. It is speculated that larger doses of naloxone might be required to produce modification of the psychostimulant effects.
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Huey, L.Y., Janowsky, D.S., Judd, L.L. et al. The effects of naloxone on methylphenidate-induced mood and behavioral changes: A negative study. Psychopharmacology 67, 125–130 (1980). https://doi.org/10.1007/BF00431966
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DOI: https://doi.org/10.1007/BF00431966