, Volume 87, Issue 2, pp 127–129 | Cite as

Central muscarinic receptors and male rat sexual behavior: Facilitation by oxotremorine but not arecoline or pilocarpine in methscopolamine pretreated animals

  • Sven Ahlenius
  • Knut Larsson
Original Investigations


Oxotremorine (0.1–0.8 mg/kg IP), but not arecoline (12–48 mg/kg IP), or pilocarpine (5–20 mg/kg IP), reduced both the number of intromissions to ejaculation and the ejaculation latency in methscopolamine-pretreated male rats. The effects of oxotremorine, (0.4 mg/kg IP) were completely antagonized by the administration of scopolamine (0.4 mg/kg IP). Methscopolamine (3–12 mg/kg IP), or scopolamine (0.2–0.4 mg/kg IP) did not by themselves produce any statistically significant effects on male rat sexual behavior.

Key words

Sexual behavior CNS Muscarinic receptors Male rat 


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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • Sven Ahlenius
    • 1
  • Knut Larsson
    • 2
  1. 1.Research and Development Laboratories, PharmacologyAstra Läkemedel ABSödertäljeSweden
  2. 2.Department of PsychologyUniversity of GöteborgGöteborgSweden

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