Abstract
Piracetam was compared with placebo in a double-blind cross-over study of 30 learning-disabled boys. Power spectral analyses revealed that piracetam caused a decrease in the amount of delta activity and an increase in the average EEG frequency. This result is in agreement with those obtained by other workers in adult patients. Some clinical effects of piracetam may be mediated by increased alertness and/or decreased fatigue.
Similar content being viewed by others
References
Bente D, Glatthaar G, Ulrich G, Lewinsky M (1978) Piracetam and vigilance: Electroencephalographic and clinical results of longterm therapy in gerontopsychiatric patients. Arzneim Forsch 28-2:1529–1531
Benton AL (1975) Developmental dyslexia: Neurological aspects. In: Friedlander WJ (ed) Advances in neurology, vol 7. Raven Press, New York, p 26
Cohen J, Cohen P (1975) Applied multiple regression/correlation analysis for the behavioral sciences. Wiley and Sons, New York, pp 173, 345 and 403
Isaksson A, Lagergren K, Wennberg A (1975) Interaction between heart and spectral parameters of the EEG: A pilot study on piracetam-treated patients with cardiac pacemakers. In: Matejcek M, Schenk GK (eds) Quantitative analysis of the EEG. AEG-Telefunken, p 149
Kunneke PS, Malan GM (1980) A controlled clinical trial on the effect of piracetam in epileptic children. Brit J Clin Practice (in press)
Maritz NG, Muller FO, Pompe van Meerdervoort HF (1978) Piracetam in the management of spasticity in cerebral plasy. S Afr Med J 53:889–891
Misurec J, Strnad P (1980) Piracetam (Nootropil) in posttraumaticol neurasthenic syndrome with lowered vigility level in the EEG. Abstracts of the 12th CINP Congress, Pergamon Press, Oxford, p 243
Satterfield JH, Cantwell DP, Lesser LI, Podosin RL (1972) Physiological studies of the hyperkinetic child. Am J Psychiatry 128:1418–1424
Simeon J, Waters B, Resnick M, Fiedorowicz C, Trites R, Volavka J, Simeon S (1980) Effects of piracetam in children with learning disorders. Psychopharmacol Bull 16:65–66
Strehl W, Brosswitz A (1972) Clinical observations with regard to the effects of UCB 6215 on some brain functions in school children (in German). Therapiewoche 22/36:2976–2979
Vencovsky E, Hronck J, Drahokoupil L, Fait V, Hudcova T, Laciga Z, Vankova H (1980) Clinical experience with treatment by piracetam in gerontopsychiatry. Ces Psychiatr 76:89–9
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Volavka, J., Simeon, J., Simeon, S. et al. Effect of piracetam on EEG spectra of boys with learning disorders. Psychopharmacology 72, 185–188 (1981). https://doi.org/10.1007/BF00431654
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00431654