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HLA antigens-risk factors for primary open-angle glaucoma?

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Summary

The comparison of the HLA A, B, and C phenotypes of 70 patients with primary open-angle glaucoma (POAG) with the phenotypes of 450 healthy control individuals and the rather discordant data published by other investigators show that there is no genetical influence of HLA A, HLA B, or HLA C genes on POAG and on the clinical complications associated with this disease.

Zusammenfassung

Der Vergleich der HLA A, B und C Phänotypen von 70 Patienten mit primärem Offenwinkelglaukom mit den Phänotypen von 450 gesunden Kontrollpersonen sowie die eher diskordanten Ergebnisse anderer Arbeitsgruppen zeigen, daß sich kein genetischer Einfluß von HLA A, HLA B oder HLA C Genen auf das primäre Offenwinkelglaukom oder die klinischen Komplikationen im Gefolge der Erkrankung nachweisen läßt.

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Authors and Affiliations

  1. Institute for Blood Group Serology of the University of Vienna, Austria

    Wolfgang R. Mayr

  2. II. Eye Department of the University of Vienna, Alserstr. 4, A-1090, Vienna, Austria

    Günther Grabner

Authors
  1. Wolfgang R. Mayr
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  2. Günther Grabner
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Additional information

National Blood Group Reference Laboratory (WHO) and National Tissue Typing Reference Laboratory (Council of Europe)

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Mayr, W.R., Grabner, G. HLA antigens-risk factors for primary open-angle glaucoma?. Albrecht von Graefes Arch. Klin. Ophthalmol. 207, 291–297 (1978). https://doi.org/10.1007/BF00431167

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  • DOI: https://doi.org/10.1007/BF00431167

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