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Differences in microcalcification in breast tumors

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Summary

Microcalcifications in benign and malignant tumors can be analyzed by X-ray diffraction and electron microprobe analysis in human specimen. Our systematic investigations revealed calcium hydroxyapatite in cases of invasive carcinoma but calcium oxalate (weddelite) in proliferating but non-invasive diseases. The differences in calcification depending on the underlying disease may indicate basic differences in cell metabolism.

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Authors and Affiliations

  1. Pathologisches Institut, Klinikum der Stadt Mannheim, Theodor-Kutzer-Ufer, D-6800, Mannheim 1, Federal Republic of Germany

    Carl Michael Büsing

  2. Laboratory for Materials Research, D-7036, Schönaich, Federal Republic of Germany

    Ulrich Keppler

  3. Central Institute for Radiology, Theresien-Krankenhaus, Mannheim, Federal Republic of Germany

    Volker Menges

Authors
  1. Carl Michael Büsing
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  2. Ulrich Keppler
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  3. Volker Menges
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Büsing, C.M., Keppler, U. & Menges, V. Differences in microcalcification in breast tumors. Virchows Arch. A Path. Anat. and Histol. 393, 307–313 (1981). https://doi.org/10.1007/BF00430830

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  • DOI: https://doi.org/10.1007/BF00430830

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