Summary
We report a case of eosinophilic gastroenterocolitis in a 2-year-old child with extensive fibrosis, atrophy of the muscularis propria and involvement of stomach, small bowel and colon. Following an attack of acute gastroenteritis at the age of 15 months the symptoms of ileus persisted. A biopsy of small bowel at the age of 18 months showed numerous eosinophilic granulocytes in the mucosa. At the age of 28 months the child died with paralytic ileus. This is the first case known to us of an eosinophilic gastroenteritis in early childhood with a fatal outcome.
Similar content being viewed by others
References
Dobbins, J.W., Sheahan, D.G., Behar, J.: Eosinophilic gastroenteritis with esophageal involvement. Gastroenterology 72, 1312–1316 (1977)
Gregg, J.A., Litz, D.D.: Eosinophilic cystitis. Associated with eosinophilic gastroenteritis. Mayo Clin. Proc. 49, 185–187 (1974)
Johnstone, J.M., Morson, B.C.: Eosinophilic gastroenteritis. Histopathology 2, 335–348 (1978)
Jona, J.Z., Belin, R.P., Burke, J.A.: Eosinophilic infiltration of the gastrointestinal tract in children. Am. J. Dis. Child 130, 1136–1139 (1976)
Katz, A.J., Goldman, H., Grand, R.J.: Gastric mucosal biopsy in eosinophilic (allergic) gastroenteritis. Gastroenterology 72, 705–709 (1977)
Klein, N.C., Hargrove, R.L., Sleisenger, M.H., Jeffries, G.H.: Eosinophilic gastroenteritis. Medicine 49, 299–319 (1970)
Landres, R.T., Kuster, G.G.R., Strum, W.B.: Eosinophilic esophagitis in a patient with vigorous achalasia. Gastroenterology 74, 1298–1301 (1978)
McGreevy, P., Doberneck, R.C., McLeary, J.N., Miller, F.A.: Recurrent eosinophilic infiltrate of the ileum causing intussusception in a 2-year-old child. Surgery 61, 280–284 (1967)
Morson, B.C., Dawson, I.M.P.: Eosinophilic lesions in the small bowel. In: Gastrointestinal pathology. Oxford: Blackwell Scientific Publications, 1972
Palubinskas, A.J.: Eosinophilic cystitis. Radiology 75, 589–591 (1960)
Samter, T.G., Alstott, D.F., Kurlander, G.J.: Inflammatory fibroid polyps of the gastrointestinal tract. Am. J. Clin. Pathol. 45, 420–435 (1966)
Toole, H.J., Moschopoulos, A.N.: Eosinophilic granuloma of the gastrointestinal tract. Br. J. Surg. 46, 445–448 (1959)
Tytgat, G.N., Grijm, R., Dekker, W., den Hartog, N.A.: Fatal eosinophilic enteritis. Gastroenterology 71, 479–483 (1976)
Waldmann, T.A., Wochner, R.D., Laster, L., Gordon, R.S.: Allergic gastroenteropathy. A cause of excessive gastrointestinal protein loss. New Engl. J. Med. 276, 761–769 (1967)
Welti, H., Parades, B., de Granière, P.: Volumineux fibrome de l'oesophage ayant simulé chez un enfant de douze ans une dyskinesie avec anorexie mentale. Arch. Mal. App. Digest. 49, 592–598 (1960)
Author information
Authors and Affiliations
Additional information
We are obliged to PD Dr. A.M. Holschneider, Univ.-Kinderklinik München for clinical data
Rights and permissions
About this article
Cite this article
Konrad, E.A., Meister, P. Fatal eosinophilic gastroenterocolitis in a two-year-old child. Virchows Arch. A Path. Anat. and Histol. 382, 347–353 (1979). https://doi.org/10.1007/BF00430410
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00430410