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Early (Stage A) prostatic cancer

IV. Methodological criteria for histopathological diagnosis

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Summary

This study was performed in order to elucidate some of the problems of incidence, morphology and natural history concerned with Stage A prostatic cancer or prostatic microcarcinoma (PMC).

The prostates of 100 patients, treated by subtotal prostatectomy for benign prostatic hyperplasia (BPH), were studied by comparing both routine and step-section techniques. The incidence of PMC was 41% by the former and 86% by the latter technique. Assessment of the size of PMC, as measured by the sum of the two main diameters, resulted in three groups: A1, A2, A3. The last of these may represent a frankly malignant condition, judged by size and the histological appearance. Radical prostatectomy is strongly suggested as appropriate therapy for this group.

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  1. Istituto di Anatomia e Istologia Patologica dell'Università di Modena, I-41100, Modena, Italy

    Salvatore Battaglia, Giuseppe Barbolini & Annibale R. Botticelli

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  1. Salvatore Battaglia
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  2. Giuseppe Barbolini
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Supported in part by a Grant from the Ministry of Education (art. 286 T.U., 1977/78)

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Battaglia, S., Barbolini, G. & Botticelli, A.R. Early (Stage A) prostatic cancer. Virchows Arch. A Path. Anat. and Histol. 382, 245–259 (1979). https://doi.org/10.1007/BF00430401

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