Summary
Plasma insulin and growth hormone levels were measured during morning and afternoon oral glucose tolerance tests performed on 12 young men at three monthly intervals in the Antarctic. No diurnal or seasonal differences in growth hormone levels were found. However there were diurnal and seasonal variations in the blood glucose/plasma insulin relationship.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Björntörp, P., de Lounge, K., Sjöström, L., Sullivan, L.: The effect of physical training on insulin production in obesity. Metabolism 19, 631–638 (1970)
Campbell, I. T., Jarrett, R. J., Keen, H.: Diurnal and seasonal variation in oral glucose tolerance: Studies in the antarctic. Diabetologia 11, 139–145 (1975)
Carroll, K. F., Nestel, P. J.: Diurnal variation in glucose tolerance and in insulin secretion in man. Diabetes 22, 333–348 (1973)
Castro, A., Scott, J. P., Grettie, D. P., Macfarlane, D., Bailey, R. E.: Plasma insulin and glucose responses of healthy subjects to varying glucose loads during three-hour oral glucose tolerance tests. Diabetes 19, 842–851 (1970)
Christensen, N. J., ørskov, H., Hansen, A. P.: Significance of glucose load in oral glucose tolerance tests. Acta. med. scand. 192, 337–342 (1972)
Hartog, M., Gaafar, M. A., Meissner, B., Fraser, R.: Immunoassay of serum growth hormone in acromegalic patients. Brit. med. J. 1964 II, 1229–1232
Jarrett, R. J., Baker, I. A., Keen, H., Oakley, N. W.: Diurnal variation in oral glucose tolerance: blood sugar and plasma insulin levels morning, afternoon and evening. Brit. med. J. 1972 I, 199–201
McIntyre, N., Holdsworth, C. D., Turner, D. S.: New interpretation of oral glucose tolerance. Lancet 1964 II, 20–21
Morgan, C. R., Lazarow, A.: Immunoassay of insulin with a two antibody system. Plasma insulin levels of normal, subdiabetic and diabetic rats. Diabetes 12, 115–126 (1963)
Oakley, N. W., Monier, D., Wynn, V.: Diurnal variation in oral glucose tolerance: insulin and growth hormone changes with special reference to women taking oral contraceptives. Diabetologia 9, 235–238 (1973)
Zimmet, P. Z., Wall, J. R., Rome, R., Stimmler, L., Jarrett, R. J.: Diurnal variation in glucose tolerance: associated changes in plasma insulin, growth hormone, and non esterifled fatty acids. Brit. med. J. 1974 I, 485–488
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Campbell, I.T., Jarrett, R.J., Rutland, P. et al. The plasma insulin and growth hormone response to oral glucose: Diurnal and seasonal observations in the antarctic. Diabetologia 11, 147–150 (1975). https://doi.org/10.1007/BF00429839
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00429839