Abstract
The administration of shock during 45–55 days after birth had a long lasting influence on the behavior of adult rats, as measured by three different tests. Shocked rats behaved more fearfully even 4 months after the infantile treatment. Chlorpromazine had no protective effect; on the contrary, it had by itself a deleterious influence on later behavior. These data suggest that the second month of life is a susceptible period, for inducing behavioral changes in adult life not only through aversive stimuli but also by the administration of pharmacological agents.
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With a fellowship from FundaÇÃo de Amparo â Pesquisa do Estado de SÃo Paulo (FAPESP).
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Masur, J., MÄrtz, R.M.W. Failure of chlorpromazine to protect rats against the effects of shock administration during the second month of life. Psychopharmacologia 28, 301–307 (1973). https://doi.org/10.1007/BF00429310
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DOI: https://doi.org/10.1007/BF00429310