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Persistence of abnormal REM sleep response to ethanol as a result of previous ethanol ingestion

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Abstract

Ethanol was administered to Sprague-Dawley rats for 4–6 weeks following which these animals thrived in a manner comparable to a naive control group. Over 6 months after an ethanol-free interval, the alcohol-exposed animals responded to a test dose of ethanol with a greater disturbance in REM sleep than noted in the naive group.

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Bibliography

  • Branchey, M., Rauscher, G., Kissin, B.: Modifications in the response to alcohol following the establishment of physical dependence. Psychopharamcologia (Berl.) 22, 314–322 (1971)

    Google Scholar 

  • Cochin, J., Kornetsky, C.: Development and loss of tolerance to morphine in the rat after single and multiple injections. J. Pharmacol. exp. Ther. 145, 1–10 (1964)

    Google Scholar 

  • Freund, G., Walker, D. W.: Impairmant of avoidance learning by prolonged ethanol consumption in mice. J. Pharmacol. exp. Ther. 179, 284–292 (1971)

    Google Scholar 

  • Freund, G., Walker, D. W.: Operant conditioning in mice. Life Sci. 11, 905–914 (1972)

    Google Scholar 

  • Khazan, N., Colasanti, B.: EEG correlates of morphine challenge in post-addict rats. Psychopharmacologia (Berl.) 22, 56–63 (1971)

    Google Scholar 

  • Khazan, N., Colasanti, B.: Protracted rebound in rapid eye movement sleep time and electroencephalogram voltage output in morphine-dependent rats upon withdrawal. J. Pharmacol. exp. Ther. 183, 23–30 (1972)

    Google Scholar 

  • Khazan, N., Weeks, J., Schroeder, L. A.: Electroencephalographic, electromyographic and behavioral correlates during a cycle of self-maintained morphine addiction in the rat. J. Pharmacol. exp. Ther. 155, 521–531 (1967)

    Google Scholar 

  • Mendelson, J.: Ethanol 1-C14 metabolism in alcoholics and non-alcoholics. Science 159, 319–320 (1968)

    Google Scholar 

  • Snedecor, G. W., Cochran, W. G.: Statistical Methods. Sixth Edition. Ames, Iowa: Iowa State University Press 1967

    Google Scholar 

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Gitlow, S.E., Bentkover, S.H., Dziedzic, S.W. et al. Persistence of abnormal REM sleep response to ethanol as a result of previous ethanol ingestion. Psychopharmacologia 33, 135–140 (1973). https://doi.org/10.1007/BF00429083

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  • DOI: https://doi.org/10.1007/BF00429083

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