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Performance on a verbal learning task by subjects of heavy past marijuana usage

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Abstract

Human, male subjects (Ss) from our heavy usage category were given paired associate learning in a 2×2 state-dependent learning design. No significant effects were found between marijuana and placebo groups on trials to criterion, and recall of the task seven days later was not found to be state-dependent. The results were compared to a previous study using light usage subjects that reported a state-dependent effect. The effects of Ss' past-marijuana usage history and the drug's acute effects on learning and recall were discussed.

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References

  • Bindra, D.: Stimulus change reactions to novelty and response decrement. Psychol. Rev. 66, 96–103 (1959)

    Google Scholar 

  • Bindra, D., Claus, H.: A test of the novelty-reactions interpretation of the effects of stimulus change. J. comp. physiol. Psychol. 53, 270–272 (1960)

    Google Scholar 

  • Bliss, D. K.: Dissociated learning and state-dependent retention induced by pentobarbital in Rhesus monkeys. J. comp. physiol. Psychol. 84, 149–161 (1973)

    Google Scholar 

  • Clark, L. D., Hughes, R., Nakashima, E.: Behavioural effects of marijuana: experimental studies. Arch. gen. Psychiat. 23, 193–198 (1970)

    Google Scholar 

  • Hollister, L. E., Gillespie, H. K.: Marijuana, ethanol, and dextroamphetamine: mood and mental function alterations. Arch. gen. Psychiat. 23, 199–203 (1970)

    Google Scholar 

  • Jones, R. T., Stone, G. R.: Psychological studies of marijuana and alcohol in man. Psychopharmacologia (Berl.) 18, 108–117 (1970)

    Google Scholar 

  • Lemberger, L., Silberstein, S. D., Axelrod, J., Kopin, I. J.: Marijuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man. Science 170, 1320–1322 (1970)

    Google Scholar 

  • Lemberger, L., Tamarkin, N. R., Axelrod, J., Kopin, I. J.: Delta-9-tetrahydrocannabinol: metabolism and disposition in long term marijuana smokers. Science 173, 72–74 (1971)

    Google Scholar 

  • Meyer, R. E., Pillard, R. C., Shapiro, L. M., Marin, S.: Administration of marijuana to heavy and causal users. Amer. J. Psychiat. 128, 198–204 (1971)

    Google Scholar 

  • Otis, L. S.: Drive Conditioning: fear as a response to biogenic drive stimuli previously associated with noxious stimuli. Amer. Psychol. 11, 297 (1956)

    Google Scholar 

  • Overton, D. A.: Discriminative control of behavior by drug states. In: Stimulus properties of drug, T. Thompson and I. Pickens, eds., pp. 83–110. New York: Appleton-Century-Crofts 1971

    Google Scholar 

  • Rickles, W. H., Cohen, M. J., Whitaker, C. A., McIntyre, K. E.: Marijuana induced state-dependent verbal learning. Psychopharmacologia (Berl.) 30, 349–354 (1973)

    Google Scholar 

  • Spear, N. E.: Retrieval of memory in animals. Psychol. Rev. 80, 163–194 (1973)

    Google Scholar 

  • Weil, A., Zinberg, N., Nelson, J.: Clinical and psychological effects of marijuana in man. Science 162, 1234–1242 (1968)

    Google Scholar 

Download references

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Supported by NIH Grant 5 R01 MH 19488-02. Computing assistance was obtained from the Health Sciences Computing Facility, UCLA, sponsored by NIH Special Resources Grant RR-3.

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Cohen, M.J., Rickles, W.H. Performance on a verbal learning task by subjects of heavy past marijuana usage. Psychopharmacologia 37, 323–330 (1974). https://doi.org/10.1007/BF00428918

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  • DOI: https://doi.org/10.1007/BF00428918

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