Summary
DNA synthesis in a thymine-requiring Escherichia coli K12 strain was studied by exploiting deoxyguanosine, so simulating the behaviour of Thy+ strains. DNA synthesis is inhibited during the first 25 min after a nutritional shift-up. The new DNA/mass is lower than that predicted by current models for initiation control.
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References
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Communicated by G. O'Donovan
Dedicated to the memory of Shmuel Zabrovitz, whose high spirits and good humor enabled him to complete the work while struggling with his lethal disease
Deceased
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Zaritsky, A., Zabrovitz, S. DNA synthesis in Escherichia coli during a nutritional shift-up. Molec. Gen. Genet. 181, 564–566 (1981). https://doi.org/10.1007/BF00428756
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DOI: https://doi.org/10.1007/BF00428756